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Multi‐Functional Liposome: A Powerful Theranostic Nano‐Platform Enhancing Photodynamic Therapy

Although photodynamic therapy (PDT) has promising advantages in almost non‐invasion, low drug resistance, and low dark toxicity, it still suffers from limitations in the lipophilic nature of most photosensitizers (PSs), short half‐life of PS in plasma, poor tissue penetration, and low tumor specific...

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Autores principales: Cheng, Xiamin, Gao, Jing, Ding, Yang, Lu, Yao, Wei, Qiancheng, Cui, Dezhi, Fan, Jiali, Li, Xiaoman, Zhu, Ershu, Lu, Yongna, Wu, Qiong, Li, Lin, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373168/
https://www.ncbi.nlm.nih.gov/pubmed/34085415
http://dx.doi.org/10.1002/advs.202100876
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author Cheng, Xiamin
Gao, Jing
Ding, Yang
Lu, Yao
Wei, Qiancheng
Cui, Dezhi
Fan, Jiali
Li, Xiaoman
Zhu, Ershu
Lu, Yongna
Wu, Qiong
Li, Lin
Huang, Wei
author_facet Cheng, Xiamin
Gao, Jing
Ding, Yang
Lu, Yao
Wei, Qiancheng
Cui, Dezhi
Fan, Jiali
Li, Xiaoman
Zhu, Ershu
Lu, Yongna
Wu, Qiong
Li, Lin
Huang, Wei
author_sort Cheng, Xiamin
collection PubMed
description Although photodynamic therapy (PDT) has promising advantages in almost non‐invasion, low drug resistance, and low dark toxicity, it still suffers from limitations in the lipophilic nature of most photosensitizers (PSs), short half‐life of PS in plasma, poor tissue penetration, and low tumor specificity. To overcome these limitations and enhance PDT, liposomes, as excellent multi‐functional nano‐carriers for drug delivery, have been extensively studied in multi‐functional theranostics, including liposomal PS, targeted drug delivery, controllable drug release, image‐guided therapy, and combined therapy. This review provides researchers with a useful reference in liposome‐based drug delivery.
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spelling pubmed-83731682021-08-24 Multi‐Functional Liposome: A Powerful Theranostic Nano‐Platform Enhancing Photodynamic Therapy Cheng, Xiamin Gao, Jing Ding, Yang Lu, Yao Wei, Qiancheng Cui, Dezhi Fan, Jiali Li, Xiaoman Zhu, Ershu Lu, Yongna Wu, Qiong Li, Lin Huang, Wei Adv Sci (Weinh) Reviews Although photodynamic therapy (PDT) has promising advantages in almost non‐invasion, low drug resistance, and low dark toxicity, it still suffers from limitations in the lipophilic nature of most photosensitizers (PSs), short half‐life of PS in plasma, poor tissue penetration, and low tumor specificity. To overcome these limitations and enhance PDT, liposomes, as excellent multi‐functional nano‐carriers for drug delivery, have been extensively studied in multi‐functional theranostics, including liposomal PS, targeted drug delivery, controllable drug release, image‐guided therapy, and combined therapy. This review provides researchers with a useful reference in liposome‐based drug delivery. John Wiley and Sons Inc. 2021-06-03 /pmc/articles/PMC8373168/ /pubmed/34085415 http://dx.doi.org/10.1002/advs.202100876 Text en © 2021 The Authors. Advanced Science published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Cheng, Xiamin
Gao, Jing
Ding, Yang
Lu, Yao
Wei, Qiancheng
Cui, Dezhi
Fan, Jiali
Li, Xiaoman
Zhu, Ershu
Lu, Yongna
Wu, Qiong
Li, Lin
Huang, Wei
Multi‐Functional Liposome: A Powerful Theranostic Nano‐Platform Enhancing Photodynamic Therapy
title Multi‐Functional Liposome: A Powerful Theranostic Nano‐Platform Enhancing Photodynamic Therapy
title_full Multi‐Functional Liposome: A Powerful Theranostic Nano‐Platform Enhancing Photodynamic Therapy
title_fullStr Multi‐Functional Liposome: A Powerful Theranostic Nano‐Platform Enhancing Photodynamic Therapy
title_full_unstemmed Multi‐Functional Liposome: A Powerful Theranostic Nano‐Platform Enhancing Photodynamic Therapy
title_short Multi‐Functional Liposome: A Powerful Theranostic Nano‐Platform Enhancing Photodynamic Therapy
title_sort multi‐functional liposome: a powerful theranostic nano‐platform enhancing photodynamic therapy
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373168/
https://www.ncbi.nlm.nih.gov/pubmed/34085415
http://dx.doi.org/10.1002/advs.202100876
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