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Multi‐Functional Liposome: A Powerful Theranostic Nano‐Platform Enhancing Photodynamic Therapy
Although photodynamic therapy (PDT) has promising advantages in almost non‐invasion, low drug resistance, and low dark toxicity, it still suffers from limitations in the lipophilic nature of most photosensitizers (PSs), short half‐life of PS in plasma, poor tissue penetration, and low tumor specific...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373168/ https://www.ncbi.nlm.nih.gov/pubmed/34085415 http://dx.doi.org/10.1002/advs.202100876 |
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author | Cheng, Xiamin Gao, Jing Ding, Yang Lu, Yao Wei, Qiancheng Cui, Dezhi Fan, Jiali Li, Xiaoman Zhu, Ershu Lu, Yongna Wu, Qiong Li, Lin Huang, Wei |
author_facet | Cheng, Xiamin Gao, Jing Ding, Yang Lu, Yao Wei, Qiancheng Cui, Dezhi Fan, Jiali Li, Xiaoman Zhu, Ershu Lu, Yongna Wu, Qiong Li, Lin Huang, Wei |
author_sort | Cheng, Xiamin |
collection | PubMed |
description | Although photodynamic therapy (PDT) has promising advantages in almost non‐invasion, low drug resistance, and low dark toxicity, it still suffers from limitations in the lipophilic nature of most photosensitizers (PSs), short half‐life of PS in plasma, poor tissue penetration, and low tumor specificity. To overcome these limitations and enhance PDT, liposomes, as excellent multi‐functional nano‐carriers for drug delivery, have been extensively studied in multi‐functional theranostics, including liposomal PS, targeted drug delivery, controllable drug release, image‐guided therapy, and combined therapy. This review provides researchers with a useful reference in liposome‐based drug delivery. |
format | Online Article Text |
id | pubmed-8373168 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-83731682021-08-24 Multi‐Functional Liposome: A Powerful Theranostic Nano‐Platform Enhancing Photodynamic Therapy Cheng, Xiamin Gao, Jing Ding, Yang Lu, Yao Wei, Qiancheng Cui, Dezhi Fan, Jiali Li, Xiaoman Zhu, Ershu Lu, Yongna Wu, Qiong Li, Lin Huang, Wei Adv Sci (Weinh) Reviews Although photodynamic therapy (PDT) has promising advantages in almost non‐invasion, low drug resistance, and low dark toxicity, it still suffers from limitations in the lipophilic nature of most photosensitizers (PSs), short half‐life of PS in plasma, poor tissue penetration, and low tumor specificity. To overcome these limitations and enhance PDT, liposomes, as excellent multi‐functional nano‐carriers for drug delivery, have been extensively studied in multi‐functional theranostics, including liposomal PS, targeted drug delivery, controllable drug release, image‐guided therapy, and combined therapy. This review provides researchers with a useful reference in liposome‐based drug delivery. John Wiley and Sons Inc. 2021-06-03 /pmc/articles/PMC8373168/ /pubmed/34085415 http://dx.doi.org/10.1002/advs.202100876 Text en © 2021 The Authors. Advanced Science published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Reviews Cheng, Xiamin Gao, Jing Ding, Yang Lu, Yao Wei, Qiancheng Cui, Dezhi Fan, Jiali Li, Xiaoman Zhu, Ershu Lu, Yongna Wu, Qiong Li, Lin Huang, Wei Multi‐Functional Liposome: A Powerful Theranostic Nano‐Platform Enhancing Photodynamic Therapy |
title | Multi‐Functional Liposome: A Powerful Theranostic Nano‐Platform Enhancing Photodynamic Therapy |
title_full | Multi‐Functional Liposome: A Powerful Theranostic Nano‐Platform Enhancing Photodynamic Therapy |
title_fullStr | Multi‐Functional Liposome: A Powerful Theranostic Nano‐Platform Enhancing Photodynamic Therapy |
title_full_unstemmed | Multi‐Functional Liposome: A Powerful Theranostic Nano‐Platform Enhancing Photodynamic Therapy |
title_short | Multi‐Functional Liposome: A Powerful Theranostic Nano‐Platform Enhancing Photodynamic Therapy |
title_sort | multi‐functional liposome: a powerful theranostic nano‐platform enhancing photodynamic therapy |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373168/ https://www.ncbi.nlm.nih.gov/pubmed/34085415 http://dx.doi.org/10.1002/advs.202100876 |
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