α,β-Amyrin prevents steatosis and insulin resistance in a high-fat diet-induced mouse model of NAFLD via the AMPK-mTORC1-SREBP1 signaling mechanism

Nonalcoholic fatty liver disease (NAFLD), characterized by hepatosteatosis and steatohepatitis, is intrinsically related to obesity. Our previous study reported on the anti-obese activity of α,β-amyrin (AMY), a pentacyclic triterpene isolated from Protium heptaphyllum. This study investigated its ab...

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Detalles Bibliográficos
Autores principales: de Lima, R.P., Nunes, P.I.G., Viana, A.F.S.C., de Oliveira, F.T.B., Silva, R.A.C., Alves, A.P.N.N., Viana, D.A., Fonseca, S.G.C., Carvalho, A.A., Chaves, M.H., Rao, V.S., Santos, F.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373198/
https://www.ncbi.nlm.nih.gov/pubmed/34406209
http://dx.doi.org/10.1590/1414-431X2021e11391

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