Diagnosing Pulmonary Tuberculosis by Using Sequence-Specific Purification of Urine Cell-Free DNA

Transrenal urine cell-free DNA (cfDNA) is a promising tuberculosis (TB) biomarker, but is challenging to detect because of the short length (<100 bp) and low concentration of TB-specific fragments. We aimed to improve the diagnostic sensitivity of TB urine cfDNA by increasing recovery of short fr...

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Detalles Bibliográficos
Autores principales: Oreskovic, Amy, Panpradist, Nuttada, Marangu, Diana, Ngwane, M. William, Magcaba, Zanele P., Ngcobo, Sindiswa, Ngcobo, Zinhle, Horne, David J., Wilson, Douglas P. K., Shapiro, Adrienne E., Drain, Paul K., Lutz, Barry R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Mycobacteriology and Aerobic Actinomycetes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373247/
https://www.ncbi.nlm.nih.gov/pubmed/33789959
http://dx.doi.org/10.1128/JCM.00074-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373247/
https://www.ncbi.nlm.nih.gov/pubmed/33789959
http://dx.doi.org/10.1128/JCM.00074-21

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