Serum osteoprotegerin level in hemodialysis patients using low‐flux reused dialyzer in relation to atherosclerosis

AIMS: To assess the relation of high serum OPG level and carotid atherosclerosis in maintenance hemodialysis (MHD) patients using low‐flux reused dialyzer. MATERIALS AND METHODS: We examined 209 MHD patients with and without carotid atherosclerosis (83 patients and 126 patients) to establish the rel...

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Detalles Bibliográficos
Autores principales: Do Van, Tung, Nguyen Minh, Tuan, Dao Bui Quy, Quyen, Pham Quoc, Toan, Nguyen Duy, Toan, Nguyen Trung, Kien, Nguyen Cong, Hoang, Le Thi Huong, Lan, Bui Thi Thu, Huong, Tran Viet, Tien, Do, Quyet, Can Van, Mao, Le Viet, Thang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373337/
https://www.ncbi.nlm.nih.gov/pubmed/34173983
http://dx.doi.org/10.1002/jcla.23886
Descripción
Sumario:AIMS: To assess the relation of high serum OPG level and carotid atherosclerosis in maintenance hemodialysis (MHD) patients using low‐flux reused dialyzer. MATERIALS AND METHODS: We examined 209 MHD patients with and without carotid atherosclerosis (83 patients and 126 patients) to establish the relation between OPG and atherosclerosis. RESULTS: The proportion of carotid atherosclerosis was 39.7%. The median serum OPG level was 45.3 pmol/L. Serum OPG had a good predicting value for atherosclerosis in MHD patients using low‐flux reused dialyzer (AUC = 0.934, p < 0.001, cutoff value = 43.35 pmol/L, Se = 81.3%, Sp = 90.9%). CONCLUSIONS: In this study, serum OPG had a good predicting value for atherosclerosis in MHD patients using low‐flux reused dialyzer.

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