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Single‐oocyte transcriptome analysis reveals aging‐associated effects influenced by life stage and calorie restriction
Chromosome segregation errors in oocytes lead to the production of aneuploid eggs, which are the leading cause of pregnancy loss and of several congenital diseases such as Down syndrome. The frequency of chromosome segregation errors in oocytes increases with maternal age, especially at a late stage...
Autores principales: | Mishina, Tappei, Tabata, Namine, Hayashi, Tetsutaro, Yoshimura, Mika, Umeda, Mana, Mori, Masashi, Ikawa, Yayoi, Hamada, Hiroshi, Nikaido, Itoshi, Kitajima, Tomoya S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373347/ https://www.ncbi.nlm.nih.gov/pubmed/34245092 http://dx.doi.org/10.1111/acel.13428 |
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