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Downregulation of ROR2 promotes dental pulp stem cell senescence by inhibiting STK4‐FOXO1/SMS1 axis in sphingomyelin biosynthesis

Dental pulp stem cells (DPSCs) play a vital role in tooth restoration, regeneration, and homeostasis. The link between DPSC senescence and tooth aging has been well‐recognized. ROR2 plays an important role in aging‐related gene expression. However, the expression and function of ROR2 in DPSC aging r...

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Detalles Bibliográficos
Autores principales: Dong, Xing‐yue, Huang, Yan‐xia, Yang, Zhan, Chu, Xiao‐yang, Wu, Jue, Wang, Shan, He, Xin, Gao, Chun‐Yan, Chen, Xu, Yang, Kai, Zhang, Dong‐liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373368/
https://www.ncbi.nlm.nih.gov/pubmed/34278704
http://dx.doi.org/10.1111/acel.13430