Integrating Tumor Sequencing Into Clinical Practice for Patients With Mismatch Repair-Deficient Lynch Syndrome Spectrum Cancers

Uninformative germline genetic testing presents a challenge to clinical management for patients suspected to have Lynch syndrome, a cancer predisposition syndrome caused by germline variants in the mismatch repair (MMR) genes or EPCAM. METHODS: Among a consecutive series of MMR-deficient Lynch syndr...

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Detalles Bibliográficos
Autores principales: Dixon, Katherine, Asrat, Mary-Jill, Bedard, Angela C., Binnington, Kristin, Compton, Katie, Cremin, Carol, Heidary, Nili, Lohn, Zoe, Lovick, Niki, McCullum, Mary, Mindlin, Allison, O'Loughlin, Melanie, Petersen, Tammy, Portigal-Todd, Cheryl, Scott, Jenna, St-Martin, Genevieve, Thompson, Jennifer, Turnbull, Ruth, Mung, Sze Wing, Hong, Quan, Bezeau, Marjorie, Bosdet, Ian, Tucker, Tracy, Young, Sean, Yip, Stephen, Aubertin, Gudrun, Blood, Katherine A., Nuk, Jennifer, Sun, Sophie, Schrader, Kasmintan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373535/
https://www.ncbi.nlm.nih.gov/pubmed/34397043
http://dx.doi.org/10.14309/ctg.0000000000000397

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