Comparative study of the interaction of ivermectin with proteins of interest associated with SARS-CoV-2: A computational and biophysical approach

The SARS-CoV-2 pandemic has accelerated the study of existing drugs. The mixture of homologs called ivermectin (avermectin-B1a [HB1a] + avermectin-B1b [HB1b]) has shown antiviral activity against SARS-CoV-2 in vitro. However, there are few reports on the behavior of each homolog. We investigated the...

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Detalles Bibliográficos
Autores principales: González-Paz, Lenin, Hurtado-León, María Laura, Lossada, Carla, Fernández-Materán, Francelys V., Vera-Villalobos, Joan, Loroño, Marcos, Paz, J.L., Jeffreys, Laura, Alvarado, Ysaias J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373590/
https://www.ncbi.nlm.nih.gov/pubmed/34428682
http://dx.doi.org/10.1016/j.bpc.2021.106677

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