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The origins of SARS-CoV-2: A critical review

Since the first reports of a novel severe acute respiratory syndrome (SARS)-like coronavirus in December 2019 in Wuhan, China, there has been intense interest in understanding how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in the human population. Recent debate has coalesce...

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Detalles Bibliográficos
Autores principales: Holmes, Edward C., Goldstein, Stephen A., Rasmussen, Angela L., Robertson, David L., Crits-Christoph, Alexander, Wertheim, Joel O., Anthony, Simon J., Barclay, Wendy S., Boni, Maciej F., Doherty, Peter C., Farrar, Jeremy, Geoghegan, Jemma L., Jiang, Xiaowei, Leibowitz, Julian L., Neil, Stuart J.D., Skern, Tim, Weiss, Susan R., Worobey, Michael, Andersen, Kristian G., Garry, Robert F., Rambaut, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373617/
https://www.ncbi.nlm.nih.gov/pubmed/34480864
http://dx.doi.org/10.1016/j.cell.2021.08.017
Descripción
Sumario:Since the first reports of a novel severe acute respiratory syndrome (SARS)-like coronavirus in December 2019 in Wuhan, China, there has been intense interest in understanding how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in the human population. Recent debate has coalesced around two competing ideas: a “laboratory escape” scenario and zoonotic emergence. Here, we critically review the current scientific evidence that may help clarify the origin of SARS-CoV-2.