The origins of SARS-CoV-2: A critical review

Since the first reports of a novel severe acute respiratory syndrome (SARS)-like coronavirus in December 2019 in Wuhan, China, there has been intense interest in understanding how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in the human population. Recent debate has coalesce...

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Autores principales: Holmes, Edward C., Goldstein, Stephen A., Rasmussen, Angela L., Robertson, David L., Crits-Christoph, Alexander, Wertheim, Joel O., Anthony, Simon J., Barclay, Wendy S., Boni, Maciej F., Doherty, Peter C., Farrar, Jeremy, Geoghegan, Jemma L., Jiang, Xiaowei, Leibowitz, Julian L., Neil, Stuart J.D., Skern, Tim, Weiss, Susan R., Worobey, Michael, Andersen, Kristian G., Garry, Robert F., Rambaut, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Inc. 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373617/
https://www.ncbi.nlm.nih.gov/pubmed/34480864
http://dx.doi.org/10.1016/j.cell.2021.08.017
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author Holmes, Edward C.
Goldstein, Stephen A.
Rasmussen, Angela L.
Robertson, David L.
Crits-Christoph, Alexander
Wertheim, Joel O.
Anthony, Simon J.
Barclay, Wendy S.
Boni, Maciej F.
Doherty, Peter C.
Farrar, Jeremy
Geoghegan, Jemma L.
Jiang, Xiaowei
Leibowitz, Julian L.
Neil, Stuart J.D.
Skern, Tim
Weiss, Susan R.
Worobey, Michael
Andersen, Kristian G.
Garry, Robert F.
Rambaut, Andrew
author_facet Holmes, Edward C.
Goldstein, Stephen A.
Rasmussen, Angela L.
Robertson, David L.
Crits-Christoph, Alexander
Wertheim, Joel O.
Anthony, Simon J.
Barclay, Wendy S.
Boni, Maciej F.
Doherty, Peter C.
Farrar, Jeremy
Geoghegan, Jemma L.
Jiang, Xiaowei
Leibowitz, Julian L.
Neil, Stuart J.D.
Skern, Tim
Weiss, Susan R.
Worobey, Michael
Andersen, Kristian G.
Garry, Robert F.
Rambaut, Andrew
author_sort Holmes, Edward C.
collection PubMed
description Since the first reports of a novel severe acute respiratory syndrome (SARS)-like coronavirus in December 2019 in Wuhan, China, there has been intense interest in understanding how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in the human population. Recent debate has coalesced around two competing ideas: a “laboratory escape” scenario and zoonotic emergence. Here, we critically review the current scientific evidence that may help clarify the origin of SARS-CoV-2.
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spelling pubmed-83736172021-08-19 The origins of SARS-CoV-2: A critical review Holmes, Edward C. Goldstein, Stephen A. Rasmussen, Angela L. Robertson, David L. Crits-Christoph, Alexander Wertheim, Joel O. Anthony, Simon J. Barclay, Wendy S. Boni, Maciej F. Doherty, Peter C. Farrar, Jeremy Geoghegan, Jemma L. Jiang, Xiaowei Leibowitz, Julian L. Neil, Stuart J.D. Skern, Tim Weiss, Susan R. Worobey, Michael Andersen, Kristian G. Garry, Robert F. Rambaut, Andrew Cell Review Since the first reports of a novel severe acute respiratory syndrome (SARS)-like coronavirus in December 2019 in Wuhan, China, there has been intense interest in understanding how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in the human population. Recent debate has coalesced around two competing ideas: a “laboratory escape” scenario and zoonotic emergence. Here, we critically review the current scientific evidence that may help clarify the origin of SARS-CoV-2. The Author(s). Published by Elsevier Inc. 2021-09-16 2021-08-19 /pmc/articles/PMC8373617/ /pubmed/34480864 http://dx.doi.org/10.1016/j.cell.2021.08.017 Text en © 2021 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review
Holmes, Edward C.
Goldstein, Stephen A.
Rasmussen, Angela L.
Robertson, David L.
Crits-Christoph, Alexander
Wertheim, Joel O.
Anthony, Simon J.
Barclay, Wendy S.
Boni, Maciej F.
Doherty, Peter C.
Farrar, Jeremy
Geoghegan, Jemma L.
Jiang, Xiaowei
Leibowitz, Julian L.
Neil, Stuart J.D.
Skern, Tim
Weiss, Susan R.
Worobey, Michael
Andersen, Kristian G.
Garry, Robert F.
Rambaut, Andrew
The origins of SARS-CoV-2: A critical review
title The origins of SARS-CoV-2: A critical review
title_full The origins of SARS-CoV-2: A critical review
title_fullStr The origins of SARS-CoV-2: A critical review
title_full_unstemmed The origins of SARS-CoV-2: A critical review
title_short The origins of SARS-CoV-2: A critical review
title_sort origins of sars-cov-2: a critical review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373617/
https://www.ncbi.nlm.nih.gov/pubmed/34480864
http://dx.doi.org/10.1016/j.cell.2021.08.017
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