Cargando…
Key features of the environment promoting liver cancer in the absence of cirrhosis
The prevalence of obesity and non-alcoholic fatty liver disease (NAFLD) associated hepatocellular carcinoma (HCC) is rising, even in the absence of cirrhosis. We aimed to develop a murine model that would facilitate further understanding of NAFLD-HCC pathogenesis. A total of 144 C3H/He mice were fed...
Autores principales: | Zaki, Marco Youssef William, Mahdi, Ahmed Khairallah, Patman, Gillian Lucinda, Whitehead, Anna, Maurício, João Pais, McCain, Misti Vanette, Televantou, Despina, Abou-Beih, Sameh, Ramon-Gil, Erik, Watson, Robyn, Cox, Charlotte, Leslie, Jack, Wilson, Caroline, Govaere, Olivier, Lunec, John, Mann, Derek Austin, Nakjang, Sirintra, Oakley, Fiona, Shukla, Ruchi, Anstee, Quentin Mark, Tiniakos, Dina, Reeves, Helen Louise |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373870/ https://www.ncbi.nlm.nih.gov/pubmed/34408183 http://dx.doi.org/10.1038/s41598-021-96076-2 |
Ejemplares similares
-
Sulfatase-2 from Cancer Associated Fibroblasts: An Environmental Target for Hepatocellular Carcinoma?
por: Zaki, Marco Y.W., et al.
Publicado: (2022) -
Sinusoidal and pericellular fibrosis in adult post-transplant liver biopsies: association with hepatic stellate cell activation and patient outcome
por: Abou-Beih, Sameh, et al.
Publicado: (2019) -
Impact of retrotransposon protein L1 ORF1p expression on oncogenic pathways in hepatocellular carcinoma: the role of cytoplasmic PIN1 upregulation
por: Zadran, Bassier, et al.
Publicado: (2023) -
The CCR2(+) Macrophage Subset Promotes Pathogenic Angiogenesis for Tumor Vascularization in Fibrotic Livers
por: Bartneck, Matthias, et al.
Publicado: (2018) -
A PDCD1 Role in the Genetic Predisposition to NAFLD-HCC?
por: Eldafashi, Nardeen, et al.
Publicado: (2021)