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Optimizing cerebral perfusion and hemodynamics during cardiopulmonary bypass through cannula design combining in silico, in vitro and in vivo input

Cardiopulmonary bypass (CPB) is a standard technique for cardiac surgery, but comes with the risk of severe neurological complications (e.g. stroke) caused by embolisms and/or reduced cerebral perfusion. We report on an aortic cannula prototype design (optiCAN) with helical outflow and jet-splitting...

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Detalles Bibliográficos
Autores principales:	Hugenroth, Kristin, Borchardt, Ralf, Ritter, Philine, Groß-Hardt, Sascha, Meyns, Bart, Verbelen, Tom, Steinseifer, Ulrich, Kaufmann, Tim A. S., Engelmann, Ulrich M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373878/ https://www.ncbi.nlm.nih.gov/pubmed/34408243 http://dx.doi.org/10.1038/s41598-021-96397-2

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