Preparation of siRNA–PLGA/Fabʹ–PLGA mixed micellar system with target cell-specific recognition

Small interfering RNAs (siRNAs) are susceptible to nucleases and degrade quickly in vivo. Moreover, siRNAs demonstrate poor cellular uptake and cannot cross the cell membrane because of its polyanionic characteristics. To overcome these challenges, an intelligent gene delivery system that protects s...

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Detalles Bibliográficos
Autores principales: Hazekawa, Mai, Nishinakagawa, Takuya, Mori, Takeshi, Yoshida, Miyako, Uchida, Takahiro, Ishibashi, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373956/
https://www.ncbi.nlm.nih.gov/pubmed/34408228
http://dx.doi.org/10.1038/s41598-021-96245-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373956/
https://www.ncbi.nlm.nih.gov/pubmed/34408228
http://dx.doi.org/10.1038/s41598-021-96245-3

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