A Multi-Study Model-Based Evaluation of the Sequence of Imaging and Clinical Biomarker Changes in Huntington’s Disease

Understanding the order and progression of change in biomarkers of neurodegeneration is essential to detect the effects of pharmacological interventions on these biomarkers. In Huntington’s disease (HD), motor, cognitive and MRI biomarkers are currently used in clinical trials of drug efficacy. Here...

Descripción completa

Detalles Bibliográficos
Autores principales: Wijeratne, Peter A., Johnson, Eileanoir B., Gregory, Sarah, Georgiou-Karistianis, Nellie, Paulsen, Jane S., Scahill, Rachael I., Tabrizi, Sarah J., Alexander, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Big Data
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374237/
https://www.ncbi.nlm.nih.gov/pubmed/34423286
http://dx.doi.org/10.3389/fdata.2021.662200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374237/
https://www.ncbi.nlm.nih.gov/pubmed/34423286
http://dx.doi.org/10.3389/fdata.2021.662200

Ejemplares similares