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A Multi-Study Model-Based Evaluation of the Sequence of Imaging and Clinical Biomarker Changes in Huntington’s Disease
Understanding the order and progression of change in biomarkers of neurodegeneration is essential to detect the effects of pharmacological interventions on these biomarkers. In Huntington’s disease (HD), motor, cognitive and MRI biomarkers are currently used in clinical trials of drug efficacy. Here...
Autores principales: | Wijeratne, Peter A., Johnson, Eileanoir B., Gregory, Sarah, Georgiou-Karistianis, Nellie, Paulsen, Jane S., Scahill, Rachael I., Tabrizi, Sarah J., Alexander, Daniel C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374237/ https://www.ncbi.nlm.nih.gov/pubmed/34423286 http://dx.doi.org/10.3389/fdata.2021.662200 |
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