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A method to establish a chronic restraint stress mouse model with colorectal cancer xenografts
Colorectal cancer (CRC) remains one of the most common clinical cancers of digestive tract. Recently, a large number of researches have shown that chronic stress can actively participate in the development of CRC. The proposed method successfully established the model of chronic stress mouse model w...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374275/ https://www.ncbi.nlm.nih.gov/pubmed/34434824 http://dx.doi.org/10.1016/j.mex.2021.101304 |
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author | Shao, Shiyun Zhang, Zhaozhou Zhang, Yingru Jia, Ru Zhao, Yiyang Li, Qi Wang, Yan |
author_facet | Shao, Shiyun Zhang, Zhaozhou Zhang, Yingru Jia, Ru Zhao, Yiyang Li, Qi Wang, Yan |
author_sort | Shao, Shiyun |
collection | PubMed |
description | Colorectal cancer (CRC) remains one of the most common clinical cancers of digestive tract. Recently, a large number of researches have shown that chronic stress can actively participate in the development of CRC. The proposed method successfully established the model of chronic stress mouse model with colorectal cancer. • Chronic restraint stress (CRS) was used to establish chronic stress model. • CRS was combined with a colorectal cancer xenografts model. • Behavioural tests and tumour growth were used to evaluate model construction. |
format | Online Article Text |
id | pubmed-8374275 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-83742752021-08-24 A method to establish a chronic restraint stress mouse model with colorectal cancer xenografts Shao, Shiyun Zhang, Zhaozhou Zhang, Yingru Jia, Ru Zhao, Yiyang Li, Qi Wang, Yan MethodsX Method Article Colorectal cancer (CRC) remains one of the most common clinical cancers of digestive tract. Recently, a large number of researches have shown that chronic stress can actively participate in the development of CRC. The proposed method successfully established the model of chronic stress mouse model with colorectal cancer. • Chronic restraint stress (CRS) was used to establish chronic stress model. • CRS was combined with a colorectal cancer xenografts model. • Behavioural tests and tumour growth were used to evaluate model construction. Elsevier 2021-03-10 /pmc/articles/PMC8374275/ /pubmed/34434824 http://dx.doi.org/10.1016/j.mex.2021.101304 Text en © 2021 The Author(s). Published by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Method Article Shao, Shiyun Zhang, Zhaozhou Zhang, Yingru Jia, Ru Zhao, Yiyang Li, Qi Wang, Yan A method to establish a chronic restraint stress mouse model with colorectal cancer xenografts |
title | A method to establish a chronic restraint stress mouse model with colorectal cancer xenografts |
title_full | A method to establish a chronic restraint stress mouse model with colorectal cancer xenografts |
title_fullStr | A method to establish a chronic restraint stress mouse model with colorectal cancer xenografts |
title_full_unstemmed | A method to establish a chronic restraint stress mouse model with colorectal cancer xenografts |
title_short | A method to establish a chronic restraint stress mouse model with colorectal cancer xenografts |
title_sort | method to establish a chronic restraint stress mouse model with colorectal cancer xenografts |
topic | Method Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374275/ https://www.ncbi.nlm.nih.gov/pubmed/34434824 http://dx.doi.org/10.1016/j.mex.2021.101304 |
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