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A method to establish a chronic restraint stress mouse model with colorectal cancer xenografts

Colorectal cancer (CRC) remains one of the most common clinical cancers of digestive tract. Recently, a large number of researches have shown that chronic stress can actively participate in the development of CRC. The proposed method successfully established the model of chronic stress mouse model w...

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Detalles Bibliográficos
Autores principales: Shao, Shiyun, Zhang, Zhaozhou, Zhang, Yingru, Jia, Ru, Zhao, Yiyang, Li, Qi, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374275/
https://www.ncbi.nlm.nih.gov/pubmed/34434824
http://dx.doi.org/10.1016/j.mex.2021.101304
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author Shao, Shiyun
Zhang, Zhaozhou
Zhang, Yingru
Jia, Ru
Zhao, Yiyang
Li, Qi
Wang, Yan
author_facet Shao, Shiyun
Zhang, Zhaozhou
Zhang, Yingru
Jia, Ru
Zhao, Yiyang
Li, Qi
Wang, Yan
author_sort Shao, Shiyun
collection PubMed
description Colorectal cancer (CRC) remains one of the most common clinical cancers of digestive tract. Recently, a large number of researches have shown that chronic stress can actively participate in the development of CRC. The proposed method successfully established the model of chronic stress mouse model with colorectal cancer. • Chronic restraint stress (CRS) was used to establish chronic stress model. • CRS was combined with a colorectal cancer xenografts model. • Behavioural tests and tumour growth were used to evaluate model construction.
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spelling pubmed-83742752021-08-24 A method to establish a chronic restraint stress mouse model with colorectal cancer xenografts Shao, Shiyun Zhang, Zhaozhou Zhang, Yingru Jia, Ru Zhao, Yiyang Li, Qi Wang, Yan MethodsX Method Article Colorectal cancer (CRC) remains one of the most common clinical cancers of digestive tract. Recently, a large number of researches have shown that chronic stress can actively participate in the development of CRC. The proposed method successfully established the model of chronic stress mouse model with colorectal cancer. • Chronic restraint stress (CRS) was used to establish chronic stress model. • CRS was combined with a colorectal cancer xenografts model. • Behavioural tests and tumour growth were used to evaluate model construction. Elsevier 2021-03-10 /pmc/articles/PMC8374275/ /pubmed/34434824 http://dx.doi.org/10.1016/j.mex.2021.101304 Text en © 2021 The Author(s). Published by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Method Article
Shao, Shiyun
Zhang, Zhaozhou
Zhang, Yingru
Jia, Ru
Zhao, Yiyang
Li, Qi
Wang, Yan
A method to establish a chronic restraint stress mouse model with colorectal cancer xenografts
title A method to establish a chronic restraint stress mouse model with colorectal cancer xenografts
title_full A method to establish a chronic restraint stress mouse model with colorectal cancer xenografts
title_fullStr A method to establish a chronic restraint stress mouse model with colorectal cancer xenografts
title_full_unstemmed A method to establish a chronic restraint stress mouse model with colorectal cancer xenografts
title_short A method to establish a chronic restraint stress mouse model with colorectal cancer xenografts
title_sort method to establish a chronic restraint stress mouse model with colorectal cancer xenografts
topic Method Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374275/
https://www.ncbi.nlm.nih.gov/pubmed/34434824
http://dx.doi.org/10.1016/j.mex.2021.101304
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