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Unsupervised Phonocardiogram Analysis With Distribution Density Based Variational Auto-Encoders

This paper proposes an unsupervised way for Phonocardiogram (PCG) analysis, which uses a revised auto encoder based on distribution density estimation in the latent space. Auto encoders especially Variational Auto-Encoders (VAEs) and its variant β−VAE are considered as one of the state-of-the-art me...

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Autores principales: Li, Shengchen, Tian, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374324/
https://www.ncbi.nlm.nih.gov/pubmed/34422847
http://dx.doi.org/10.3389/fmed.2021.655084
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author Li, Shengchen
Tian, Ke
author_facet Li, Shengchen
Tian, Ke
author_sort Li, Shengchen
collection PubMed
description This paper proposes an unsupervised way for Phonocardiogram (PCG) analysis, which uses a revised auto encoder based on distribution density estimation in the latent space. Auto encoders especially Variational Auto-Encoders (VAEs) and its variant β−VAE are considered as one of the state-of-the-art methodologies for PCG analysis. VAE based models for PCG analysis assume that normal PCG signals can be represented by latent vectors that obey a normal Gaussian Model, which may not be necessary true in PCG analysis. This paper proposes two methods DBVAE and DBAE that are based on estimating the density of latent vectors in latent space to improve the performance of VAE based PCG analysis systems. Examining the system performance with PCG data from the a single domain and multiple domains, the proposed systems outperform the VAE based methods. The representation of normal PCG signals in the latent space is also investigated by calculating the kurtosis and skewness where DBAE introduces normal PCG representation following Gaussian-like models but DBVAE does not introduce normal PCG representation following Gaussian-like models.
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spelling pubmed-83743242021-08-20 Unsupervised Phonocardiogram Analysis With Distribution Density Based Variational Auto-Encoders Li, Shengchen Tian, Ke Front Med (Lausanne) Medicine This paper proposes an unsupervised way for Phonocardiogram (PCG) analysis, which uses a revised auto encoder based on distribution density estimation in the latent space. Auto encoders especially Variational Auto-Encoders (VAEs) and its variant β−VAE are considered as one of the state-of-the-art methodologies for PCG analysis. VAE based models for PCG analysis assume that normal PCG signals can be represented by latent vectors that obey a normal Gaussian Model, which may not be necessary true in PCG analysis. This paper proposes two methods DBVAE and DBAE that are based on estimating the density of latent vectors in latent space to improve the performance of VAE based PCG analysis systems. Examining the system performance with PCG data from the a single domain and multiple domains, the proposed systems outperform the VAE based methods. The representation of normal PCG signals in the latent space is also investigated by calculating the kurtosis and skewness where DBAE introduces normal PCG representation following Gaussian-like models but DBVAE does not introduce normal PCG representation following Gaussian-like models. Frontiers Media S.A. 2021-08-05 /pmc/articles/PMC8374324/ /pubmed/34422847 http://dx.doi.org/10.3389/fmed.2021.655084 Text en Copyright © 2021 Li and Tian. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Li, Shengchen
Tian, Ke
Unsupervised Phonocardiogram Analysis With Distribution Density Based Variational Auto-Encoders
title Unsupervised Phonocardiogram Analysis With Distribution Density Based Variational Auto-Encoders
title_full Unsupervised Phonocardiogram Analysis With Distribution Density Based Variational Auto-Encoders
title_fullStr Unsupervised Phonocardiogram Analysis With Distribution Density Based Variational Auto-Encoders
title_full_unstemmed Unsupervised Phonocardiogram Analysis With Distribution Density Based Variational Auto-Encoders
title_short Unsupervised Phonocardiogram Analysis With Distribution Density Based Variational Auto-Encoders
title_sort unsupervised phonocardiogram analysis with distribution density based variational auto-encoders
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374324/
https://www.ncbi.nlm.nih.gov/pubmed/34422847
http://dx.doi.org/10.3389/fmed.2021.655084
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