Cargando…
The role of spinal cord extrasynaptic α(5)GABA(A) receptors in chronic pain
Chronic pain is an incapacitating condition that affects a large population worldwide. Until now, there is no drug treatment to relieve it. The impairment of GABAergic inhibition mediated by GABA(A) receptors (GABA(A)R) is considered a relevant factor in mediating chronic pain. Even though both syna...
Autores principales: | Delgado‐Lezama, Rodolfo, Bravo‐Hernández, Mariana, Franco‐Enzástiga, Úrzula, De la Luz‐Cuellar, Yarim E., Alvarado‐Cervantes, Nara S., Raya‐Tafolla, Guadalupe, Martínez‐Zaldivar, Luis A., Vargas‐Parada, Alberto, Rodríguez‐Palma, Erick J., Vidal‐Cantú, Guadalupe C., Guzmán‐Priego, Crystell G., Torres‐López, Jorge E., Murbartián, Janet, Felix, Ricardo, Granados‐Soto, Vinicio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374381/ https://www.ncbi.nlm.nih.gov/pubmed/34409771 http://dx.doi.org/10.14814/phy2.14984 |
Ejemplares similares
-
GABA(B) Receptors Tonically Inhibit Motoneurons and Neurotransmitter Release from Descending and Primary Afferent Fibers
por: Delgado-Ramírez, Ximena, et al.
Publicado: (2023) -
Metformin: A Prospective Alternative for the Treatment of Chronic Pain
por: Baeza-Flores, Guadalupe Del Carmen, et al.
Publicado: (2020) -
Peripheral and spinal TRPA1 channels contribute to formalin-induced long-lasting mechanical hypersensitivity
por: Martínez-Rojas, Vladimir A, et al.
Publicado: (2017) -
Role of NHE1 in Nociception
por: Torres-López, Jorge Elías, et al.
Publicado: (2013) -
Metabotropic regulation of extrasynaptic GABA(A) receptors
por: Connelly, William M., et al.
Publicado: (2013)