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Responders and non‐responders to aerobic exercise training: beyond the evaluation of [Formula: see text]
The evaluation of the maximal oxygen uptake ([Formula: see text]) following exercise training is the classical assessment of training effectiveness. Research has lacked in investigating whether individuals that do not respond to the training intervention ([Formula: see text]), also do not improve in...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374384/ https://www.ncbi.nlm.nih.gov/pubmed/34409753 http://dx.doi.org/10.14814/phy2.14951 |
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author | Mattioni Maturana, Felipe Soares, Rogerio N. Murias, Juan M. Schellhorn, Philipp Erz, Gunnar Burgstahler, Christof Widmann, Manuel Munz, Barbara Thiel, Ansgar Nieß, Andreas M. |
author_facet | Mattioni Maturana, Felipe Soares, Rogerio N. Murias, Juan M. Schellhorn, Philipp Erz, Gunnar Burgstahler, Christof Widmann, Manuel Munz, Barbara Thiel, Ansgar Nieß, Andreas M. |
author_sort | Mattioni Maturana, Felipe |
collection | PubMed |
description | The evaluation of the maximal oxygen uptake ([Formula: see text]) following exercise training is the classical assessment of training effectiveness. Research has lacked in investigating whether individuals that do not respond to the training intervention ([Formula: see text]), also do not improve in other health‐related parameters. We aimed to investigate the cardiovascular and metabolic adaptations (i.e., performance, body composition, blood pressure, vascular function, fasting blood markers, and resting cardiac function and morphology) to exercise training among participants who showed different levels of [Formula: see text] responsiveness. Healthy sedentary participants engaged in a 6‐week exercise training program, three times a week. Our results showed that responders had a greater increase in peak power output, second lactate threshold, and microvascular responsiveness, whereas non‐responders had a greater increase in cycling efficiency. No statistical differences were observed in body composition, blood pressure, fasting blood parameters, and resting cardiac adaptations. In conclusion, our study showed, for the first time, that in addition to the differences in the [Formula: see text] , a greater increase in microvascular responsiveness in responders compared to non‐responders was observed. Additionally, responders and non‐responders did not show differences in the adaptations on metabolic parameters. There is an increasing need for personalized training prescription, depending on the target clinical outcome. |
format | Online Article Text |
id | pubmed-8374384 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-83743842021-08-26 Responders and non‐responders to aerobic exercise training: beyond the evaluation of [Formula: see text] Mattioni Maturana, Felipe Soares, Rogerio N. Murias, Juan M. Schellhorn, Philipp Erz, Gunnar Burgstahler, Christof Widmann, Manuel Munz, Barbara Thiel, Ansgar Nieß, Andreas M. Physiol Rep Original Articles The evaluation of the maximal oxygen uptake ([Formula: see text]) following exercise training is the classical assessment of training effectiveness. Research has lacked in investigating whether individuals that do not respond to the training intervention ([Formula: see text]), also do not improve in other health‐related parameters. We aimed to investigate the cardiovascular and metabolic adaptations (i.e., performance, body composition, blood pressure, vascular function, fasting blood markers, and resting cardiac function and morphology) to exercise training among participants who showed different levels of [Formula: see text] responsiveness. Healthy sedentary participants engaged in a 6‐week exercise training program, three times a week. Our results showed that responders had a greater increase in peak power output, second lactate threshold, and microvascular responsiveness, whereas non‐responders had a greater increase in cycling efficiency. No statistical differences were observed in body composition, blood pressure, fasting blood parameters, and resting cardiac adaptations. In conclusion, our study showed, for the first time, that in addition to the differences in the [Formula: see text] , a greater increase in microvascular responsiveness in responders compared to non‐responders was observed. Additionally, responders and non‐responders did not show differences in the adaptations on metabolic parameters. There is an increasing need for personalized training prescription, depending on the target clinical outcome. John Wiley and Sons Inc. 2021-08-19 /pmc/articles/PMC8374384/ /pubmed/34409753 http://dx.doi.org/10.14814/phy2.14951 Text en © 2021 The Authors. Physiological Reports published by Wiley Periodicals LLC on behalf of The Physiological Society and the American Physiological Society. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Mattioni Maturana, Felipe Soares, Rogerio N. Murias, Juan M. Schellhorn, Philipp Erz, Gunnar Burgstahler, Christof Widmann, Manuel Munz, Barbara Thiel, Ansgar Nieß, Andreas M. Responders and non‐responders to aerobic exercise training: beyond the evaluation of [Formula: see text] |
title | Responders and non‐responders to aerobic exercise training: beyond the evaluation of [Formula: see text]
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title_full | Responders and non‐responders to aerobic exercise training: beyond the evaluation of [Formula: see text]
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title_fullStr | Responders and non‐responders to aerobic exercise training: beyond the evaluation of [Formula: see text]
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title_full_unstemmed | Responders and non‐responders to aerobic exercise training: beyond the evaluation of [Formula: see text]
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title_short | Responders and non‐responders to aerobic exercise training: beyond the evaluation of [Formula: see text]
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title_sort | responders and non‐responders to aerobic exercise training: beyond the evaluation of [formula: see text] |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374384/ https://www.ncbi.nlm.nih.gov/pubmed/34409753 http://dx.doi.org/10.14814/phy2.14951 |
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