OnabotulinumtoxinA affects cortical recovery period but not occurrence or propagation of cortical spreading depression in rats with compromised blood–brain barrier

OnabotulinumtoxinA (BoNT-A) is an Food and Drug Administration-approved, peripherally acting preventive migraine drug capable of inhibiting meningeal nociceptors. Expanding our view of how else this neurotoxin attenuates the activation of the meningeal nociceptors, we reasoned that if the stimulus t...

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Detalles Bibliográficos
Autores principales: Melo-Carrillo, Agustin, Strassman, Andrew M., Schain, Aaron J., Broide, Ron S., Cai, Brian B., Rhéaume, Catherine, Brideau-Andersen, Amy D., Ashina, Sait, Flores-Montanez, Yadira, Brin, Mitchell F., Burstein, Rami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374711/
https://www.ncbi.nlm.nih.gov/pubmed/34448754
http://dx.doi.org/10.1097/j.pain.0000000000002230

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