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Cerebral Venous Sinus Thrombosis as an Unexpected Complication of COVID-19 Pneumonia
Coronavirus disease 2019 (COVID-19) is commonly associated with acute respiratory distress syndrome and acute cardiac and renal injuries. However, thromboembolic events are also prevalent in COVID-19. The pathogenesis of COVID-19 hypercoagulability is not well known but may be linked to the cytokine...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374991/ https://www.ncbi.nlm.nih.gov/pubmed/34430113 http://dx.doi.org/10.7759/cureus.16498 |
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author | Abdulgayoom, Mohammed Abdelmahmuod, Elabbass Elfaki, Ahmed Halabiya, Malik A |
author_facet | Abdulgayoom, Mohammed Abdelmahmuod, Elabbass Elfaki, Ahmed Halabiya, Malik A |
author_sort | Abdulgayoom, Mohammed |
collection | PubMed |
description | Coronavirus disease 2019 (COVID-19) is commonly associated with acute respiratory distress syndrome and acute cardiac and renal injuries. However, thromboembolic events are also prevalent in COVID-19. The pathogenesis of COVID-19 hypercoagulability is not well known but may be linked to the cytokine storm induced by a viral infection or endothelial damage that triggers a cascade leading to hypercoagulability. Because vascular endothelium has angiotensin-converting enzyme 2-like lung tissue, COVID-19 targets lung tissue and vascular endothelium, leading to thrombosis. We present a rare case of a young patient with COVID-19 who presented with thrombosis of the cerebral venous system managed with anticoagulation. This case highlights the need for heightened awareness of this atypical but potentially treatable complication of the COVID-19 disease spectrum. |
format | Online Article Text |
id | pubmed-8374991 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-83749912021-08-23 Cerebral Venous Sinus Thrombosis as an Unexpected Complication of COVID-19 Pneumonia Abdulgayoom, Mohammed Abdelmahmuod, Elabbass Elfaki, Ahmed Halabiya, Malik A Cureus Internal Medicine Coronavirus disease 2019 (COVID-19) is commonly associated with acute respiratory distress syndrome and acute cardiac and renal injuries. However, thromboembolic events are also prevalent in COVID-19. The pathogenesis of COVID-19 hypercoagulability is not well known but may be linked to the cytokine storm induced by a viral infection or endothelial damage that triggers a cascade leading to hypercoagulability. Because vascular endothelium has angiotensin-converting enzyme 2-like lung tissue, COVID-19 targets lung tissue and vascular endothelium, leading to thrombosis. We present a rare case of a young patient with COVID-19 who presented with thrombosis of the cerebral venous system managed with anticoagulation. This case highlights the need for heightened awareness of this atypical but potentially treatable complication of the COVID-19 disease spectrum. Cureus 2021-07-19 /pmc/articles/PMC8374991/ /pubmed/34430113 http://dx.doi.org/10.7759/cureus.16498 Text en Copyright © 2021, Abdulgayoom et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Abdulgayoom, Mohammed Abdelmahmuod, Elabbass Elfaki, Ahmed Halabiya, Malik A Cerebral Venous Sinus Thrombosis as an Unexpected Complication of COVID-19 Pneumonia |
title | Cerebral Venous Sinus Thrombosis as an Unexpected Complication of COVID-19 Pneumonia |
title_full | Cerebral Venous Sinus Thrombosis as an Unexpected Complication of COVID-19 Pneumonia |
title_fullStr | Cerebral Venous Sinus Thrombosis as an Unexpected Complication of COVID-19 Pneumonia |
title_full_unstemmed | Cerebral Venous Sinus Thrombosis as an Unexpected Complication of COVID-19 Pneumonia |
title_short | Cerebral Venous Sinus Thrombosis as an Unexpected Complication of COVID-19 Pneumonia |
title_sort | cerebral venous sinus thrombosis as an unexpected complication of covid-19 pneumonia |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374991/ https://www.ncbi.nlm.nih.gov/pubmed/34430113 http://dx.doi.org/10.7759/cureus.16498 |
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