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rAAV9‐mediated supplementation of miR-29b improve angiotensin-II induced renal fibrosis in mice

BACKGROUND: Renin–angiotensin–aldosterone system activation is the critical factor in renal remodeling and dysfunction. Our previous study suggested that miR-29b may attenuate AngII-induced renal intestinal fibrosis in vitro. In the present study, we aimed to determine whether recombinant rAAV9-medi...

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Detalles Bibliográficos
Autores principales: Zhang, Ju-hong, Li, Jing, Ye, Yang, Yu, Wang-qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375072/
https://www.ncbi.nlm.nih.gov/pubmed/34407760
http://dx.doi.org/10.1186/s10020-021-00349-5