A novel NF-κB regulator encoded by circPLCE1 inhibits colorectal carcinoma progression by promoting RPS3 ubiquitin-dependent degradation

BACKGROUND: Constitutive activation of nuclear factor-κB (NF-κB) signaling plays a key role in the development and progression of colorectal carcinoma (CRC). However, the underlying mechanisms of excessive activation of NF-κB signaling remain largely unknown. METHODS: We used high throughput RNA seq...

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Detalles Bibliográficos
Autores principales: Liang, Zhen-xing, Liu, Hua-shan, Xiong, Li, Yang, Xin, Wang, Feng-wei, Zeng, Zi-wei, He, Xiao-wen, Wu, Xian-rui, Lan, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375079/
https://www.ncbi.nlm.nih.gov/pubmed/34412652
http://dx.doi.org/10.1186/s12943-021-01404-9

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