Experimental colitis promotes sustained, sex-dependent, T-cell-associated neuroinflammation and parkinsonian neuropathology

BACKGROUND: The etiology of sporadic Parkinson’s disease (PD) remains uncertain, but genetic, epidemiological, and physiological overlap between PD and inflammatory bowel disease suggests that gut inflammation could promote dysfunction of dopamine-producing neurons in the brain. Mechanisms behind th...

Descripción completa

Detalles Bibliográficos
Autores principales: Houser, Madelyn C., Caudle, W. Michael, Chang, Jianjun, Kannarkat, George T., Yang, Yuan, Kelly, Sean D., Oliver, Danielle, Joers, Valerie, Shannon, Kathleen M., Keshavarzian, Ali, Tansey, Malú Gámez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375080/
https://www.ncbi.nlm.nih.gov/pubmed/34412704
http://dx.doi.org/10.1186/s40478-021-01240-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375080/
https://www.ncbi.nlm.nih.gov/pubmed/34412704
http://dx.doi.org/10.1186/s40478-021-01240-4

Ejemplares similares