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Experimental colitis promotes sustained, sex-dependent, T-cell-associated neuroinflammation and parkinsonian neuropathology

BACKGROUND: The etiology of sporadic Parkinson’s disease (PD) remains uncertain, but genetic, epidemiological, and physiological overlap between PD and inflammatory bowel disease suggests that gut inflammation could promote dysfunction of dopamine-producing neurons in the brain. Mechanisms behind th...

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Detalles Bibliográficos
Autores principales:	Houser, Madelyn C., Caudle, W. Michael, Chang, Jianjun, Kannarkat, George T., Yang, Yuan, Kelly, Sean D., Oliver, Danielle, Joers, Valerie, Shannon, Kathleen M., Keshavarzian, Ali, Tansey, Malú Gámez
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375080/ https://www.ncbi.nlm.nih.gov/pubmed/34412704 http://dx.doi.org/10.1186/s40478-021-01240-4

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