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cGMP-grade human iPSC-derived retinal photoreceptor precursor cells rescue cone photoreceptor damage in non-human primates
BACKGROUND: Retinal regenerative therapies hold great promise for the treatment of inherited retinal degenerations (IRDs). Studies in preclinical lower mammal models of IRDs have suggested visual improvement following retinal photoreceptor precursors transplantation, but there is limited evidence on...
Autores principales: | Lingam, Swathi, Liu, Zengping, Yang, Binxia, Wong, Wendy, Parikh, Bhav Harshad, Ong, Jun Yi, Goh, Debbie, Wong, Daniel Soo Lin, Tan, Queenie Shu Woon, Tan, Gavin S. W., Holder, Graham E., Regha, Kakkad, Barathi, Veluchamy Amutha, Hunziker, Walter, Lingam, Gopal, Zeng, Xianmin, Su, Xinyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375124/ https://www.ncbi.nlm.nih.gov/pubmed/34412697 http://dx.doi.org/10.1186/s13287-021-02539-8 |
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