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Human umbilical cord mesenchymal stem cells deliver exogenous miR-26a-5p via exosomes to inhibit nucleus pulposus cell pyroptosis through METTL14/NLRP3

BACKGROUND: Intervertebral disc degeneration (IVDD) is the breakdown of the discs supporting the vertebrae. It is one of the most frequent causes of back pain worldwide. Currently, the clinical interventions for IVDD are mainly focused on symptom releases. Thus, new therapeutic options are needed. M...

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Detalles Bibliográficos
Autores principales:	Yuan, Xiaoqiu, Li, Tiefeng, Shi, Lei, Miao, Jinhao, Guo, Yongfei, Chen, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375162/ https://www.ncbi.nlm.nih.gov/pubmed/34412584 http://dx.doi.org/10.1186/s10020-021-00355-7

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