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USP10 alleviates sepsis-induced acute kidney injury by regulating Sirt6-mediated Nrf2/ARE signaling pathway

BACKGROUND: Severe sepsis, a major health problem worldwide, has become one of the leading causes of death in ICU patients. Further study on the pathogenesis and treatment of acute kidney injury (AKI) is of great significance to reduce high mortality rate of sepsis. In this study, the mechanism by w...

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Detalles Bibliográficos
Autores principales: Gao, Fei, Qian, Mingjiang, Liu, Guoyue, Ao, Wanping, Dai, Dahua, Yin, Cunzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375185/
https://www.ncbi.nlm.nih.gov/pubmed/34412625
http://dx.doi.org/10.1186/s12950-021-00291-7