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Milk Fat Globule-EGF Factor 8 Alleviates Pancreatic Fibrosis by Inhibiting ER Stress-Induced Chaperone-Mediated Autophagy in Mice
Pancreatic fibrosis is an important pathophysiological feature of chronic pancreatitis (CP). Our recent study has shown that milk fat globule-EGF factor 8 (MFG-E8) is beneficial in acute pancreatitis. However, its role in CP remained unknown. To study this, CP was induced in male adult Mfge8-knockou...
Autores principales: | Ren, Yifan, Cui, Qing, Zhang, Jia, Liu, Wuming, Xu, Meng, Lv, Yi, Wu, Zheng, Zhang, Yuanyuan, Wu, Rongqian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375434/ https://www.ncbi.nlm.nih.gov/pubmed/34421598 http://dx.doi.org/10.3389/fphar.2021.707259 |
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