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Seroprevalencia de Brucella canis en perros de un refugio para animales de compañía en Bogotá, Colombia

INTRODUCTION: The risk of Brucella canis infection in humans and dogs has increased due to the permanent exposure to asymptomatic carrier dogs. In Colombia, there is evidence of B. canis infection in humans living with dogs. In the case of Bogotá, an additional concern is the lack of updated informa...

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Autores principales: Laverde, Astrid-Jullieth, Restrepo-Botero, Daniela, Hernández-Pulido, Diego, Rodríguez-Bautista, José Luis, Sandoval, Isabel-Sofía
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Nacional de Salud 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375667/
https://www.ncbi.nlm.nih.gov/pubmed/34214267
http://dx.doi.org/10.7705/biomedica.5409
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author Laverde, Astrid-Jullieth
Restrepo-Botero, Daniela
Hernández-Pulido, Diego
Rodríguez-Bautista, José Luis
Sandoval, Isabel-Sofía
author_facet Laverde, Astrid-Jullieth
Restrepo-Botero, Daniela
Hernández-Pulido, Diego
Rodríguez-Bautista, José Luis
Sandoval, Isabel-Sofía
author_sort Laverde, Astrid-Jullieth
collection PubMed
description INTRODUCTION: The risk of Brucella canis infection in humans and dogs has increased due to the permanent exposure to asymptomatic carrier dogs. In Colombia, there is evidence of B. canis infection in humans living with dogs. In the case of Bogotá, an additional concern is the lack of updated information related to the prevalence of the infection in dogs. OBJECTIVE: To determine the seroprevalence of infection by B. canis in dogs intended for adoption programs in Bogotá. MATERIALS AND METHODS: By means of a descriptive cross-sectional study carried out in a dog shelter in Bogotá, anti-B. canis IgG antibodies were detected in the serum from 51 dogs (28 females and 23 males) using a lateral-flow immunochromatographic test. Additionally, seropositive animals were analyzed with PCR to detect Brucella spp DNA. RESULTS: Brucella canis seroprevalence was 1.96% (1/51). The seropositive dog was an asymptomatic three-year-old she-dog in which no bacteria DNA was detected in the blood through PCR. CONCLUSIONS: The seroprevalence determined in this study represented by a single dog with anti-B. canis IgG can be considered a potential risk both for canine and human populations since this single dog could have a persistent infection capable of spreading the bacteria.
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spelling pubmed-83756672021-08-20 Seroprevalencia de Brucella canis en perros de un refugio para animales de compañía en Bogotá, Colombia Laverde, Astrid-Jullieth Restrepo-Botero, Daniela Hernández-Pulido, Diego Rodríguez-Bautista, José Luis Sandoval, Isabel-Sofía Biomedica Artículo Original INTRODUCTION: The risk of Brucella canis infection in humans and dogs has increased due to the permanent exposure to asymptomatic carrier dogs. In Colombia, there is evidence of B. canis infection in humans living with dogs. In the case of Bogotá, an additional concern is the lack of updated information related to the prevalence of the infection in dogs. OBJECTIVE: To determine the seroprevalence of infection by B. canis in dogs intended for adoption programs in Bogotá. MATERIALS AND METHODS: By means of a descriptive cross-sectional study carried out in a dog shelter in Bogotá, anti-B. canis IgG antibodies were detected in the serum from 51 dogs (28 females and 23 males) using a lateral-flow immunochromatographic test. Additionally, seropositive animals were analyzed with PCR to detect Brucella spp DNA. RESULTS: Brucella canis seroprevalence was 1.96% (1/51). The seropositive dog was an asymptomatic three-year-old she-dog in which no bacteria DNA was detected in the blood through PCR. CONCLUSIONS: The seroprevalence determined in this study represented by a single dog with anti-B. canis IgG can be considered a potential risk both for canine and human populations since this single dog could have a persistent infection capable of spreading the bacteria. Instituto Nacional de Salud 2021-06-25 /pmc/articles/PMC8375667/ /pubmed/34214267 http://dx.doi.org/10.7705/biomedica.5409 Text en https://creativecommons.org/licenses/by/4.0/Este es un artículo publicado en acceso abierto bajo una licencia Creative Commons
spellingShingle Artículo Original
Laverde, Astrid-Jullieth
Restrepo-Botero, Daniela
Hernández-Pulido, Diego
Rodríguez-Bautista, José Luis
Sandoval, Isabel-Sofía
Seroprevalencia de Brucella canis en perros de un refugio para animales de compañía en Bogotá, Colombia
title Seroprevalencia de Brucella canis en perros de un refugio para animales de compañía en Bogotá, Colombia
title_full Seroprevalencia de Brucella canis en perros de un refugio para animales de compañía en Bogotá, Colombia
title_fullStr Seroprevalencia de Brucella canis en perros de un refugio para animales de compañía en Bogotá, Colombia
title_full_unstemmed Seroprevalencia de Brucella canis en perros de un refugio para animales de compañía en Bogotá, Colombia
title_short Seroprevalencia de Brucella canis en perros de un refugio para animales de compañía en Bogotá, Colombia
title_sort seroprevalencia de brucella canis en perros de un refugio para animales de compañía en bogotá, colombia
topic Artículo Original
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375667/
https://www.ncbi.nlm.nih.gov/pubmed/34214267
http://dx.doi.org/10.7705/biomedica.5409
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