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To Compare and Analyze the Potency of two Topical Anesthetic Gels in Reducing Inferior Alveolar Injection Pain in Children of 8–12 Years: A Double-Blinded Clinical Trial
AIM: To compare and analyze the clinical adequacy of two topical anesthetic gels, Precaine (8% lidocaine + 0.8% dibucaine) and Precaine B (20% benzocaine) in children before intraoral local anesthetic injections. MATERIALS AND METHODS: This clinical study included thirty children who needed an infer...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375789/ https://www.ncbi.nlm.nih.gov/pubmed/34447172 http://dx.doi.org/10.4103/jpbs.JPBS_772_20 |
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author | Patel, Dharati Lahiri, Banibrata El-Patal, Mohamed Abd-Ellatif Alazmah, Abdulfatah Patel, Parth Abokhlifa, Yousef H. |
author_facet | Patel, Dharati Lahiri, Banibrata El-Patal, Mohamed Abd-Ellatif Alazmah, Abdulfatah Patel, Parth Abokhlifa, Yousef H. |
author_sort | Patel, Dharati |
collection | PubMed |
description | AIM: To compare and analyze the clinical adequacy of two topical anesthetic gels, Precaine (8% lidocaine + 0.8% dibucaine) and Precaine B (20% benzocaine) in children before intraoral local anesthetic injections. MATERIALS AND METHODS: This clinical study included thirty children who needed an inferior alveolar nerve block. They were divided into three groups: Group A: Precaine topical gel group, Group B: Precaine B topical gel Group, Group C: no anesthetic topical gel group (control group). These two effective topical gels were applied before giving intraoral local anesthesia, and afterward, the child's pain response was surveyed utilizing the Wong-Baker Faces Pain Rating Scale. The scores obtained were subjected to statistical analysis. RESULTS: Intergroup comparison showed a significant mean difference between the control group and Precaine group (P > 0.05) as well as Precaine B group (P > 0.05). However, there is no significant difference obtained between Group A and Group B (P < 0.05). CONCLUSION: It is psychologically and clinically beneficial to apply a topical anesthetic agent before injecting any intraoral anesthesia. In this study, both anesthetic gels showed a nonsignificant difference in reducing inferior alveolar injection pain, but Precaine B shows more promising results than Precaine. |
format | Online Article Text |
id | pubmed-8375789 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-83757892021-08-25 To Compare and Analyze the Potency of two Topical Anesthetic Gels in Reducing Inferior Alveolar Injection Pain in Children of 8–12 Years: A Double-Blinded Clinical Trial Patel, Dharati Lahiri, Banibrata El-Patal, Mohamed Abd-Ellatif Alazmah, Abdulfatah Patel, Parth Abokhlifa, Yousef H. J Pharm Bioallied Sci Original Article AIM: To compare and analyze the clinical adequacy of two topical anesthetic gels, Precaine (8% lidocaine + 0.8% dibucaine) and Precaine B (20% benzocaine) in children before intraoral local anesthetic injections. MATERIALS AND METHODS: This clinical study included thirty children who needed an inferior alveolar nerve block. They were divided into three groups: Group A: Precaine topical gel group, Group B: Precaine B topical gel Group, Group C: no anesthetic topical gel group (control group). These two effective topical gels were applied before giving intraoral local anesthesia, and afterward, the child's pain response was surveyed utilizing the Wong-Baker Faces Pain Rating Scale. The scores obtained were subjected to statistical analysis. RESULTS: Intergroup comparison showed a significant mean difference between the control group and Precaine group (P > 0.05) as well as Precaine B group (P > 0.05). However, there is no significant difference obtained between Group A and Group B (P < 0.05). CONCLUSION: It is psychologically and clinically beneficial to apply a topical anesthetic agent before injecting any intraoral anesthesia. In this study, both anesthetic gels showed a nonsignificant difference in reducing inferior alveolar injection pain, but Precaine B shows more promising results than Precaine. Wolters Kluwer - Medknow 2021-06 2021-06-05 /pmc/articles/PMC8375789/ /pubmed/34447172 http://dx.doi.org/10.4103/jpbs.JPBS_772_20 Text en Copyright: © 2021 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Patel, Dharati Lahiri, Banibrata El-Patal, Mohamed Abd-Ellatif Alazmah, Abdulfatah Patel, Parth Abokhlifa, Yousef H. To Compare and Analyze the Potency of two Topical Anesthetic Gels in Reducing Inferior Alveolar Injection Pain in Children of 8–12 Years: A Double-Blinded Clinical Trial |
title | To Compare and Analyze the Potency of two Topical Anesthetic Gels in Reducing Inferior Alveolar Injection Pain in Children of 8–12 Years: A Double-Blinded Clinical Trial |
title_full | To Compare and Analyze the Potency of two Topical Anesthetic Gels in Reducing Inferior Alveolar Injection Pain in Children of 8–12 Years: A Double-Blinded Clinical Trial |
title_fullStr | To Compare and Analyze the Potency of two Topical Anesthetic Gels in Reducing Inferior Alveolar Injection Pain in Children of 8–12 Years: A Double-Blinded Clinical Trial |
title_full_unstemmed | To Compare and Analyze the Potency of two Topical Anesthetic Gels in Reducing Inferior Alveolar Injection Pain in Children of 8–12 Years: A Double-Blinded Clinical Trial |
title_short | To Compare and Analyze the Potency of two Topical Anesthetic Gels in Reducing Inferior Alveolar Injection Pain in Children of 8–12 Years: A Double-Blinded Clinical Trial |
title_sort | to compare and analyze the potency of two topical anesthetic gels in reducing inferior alveolar injection pain in children of 8–12 years: a double-blinded clinical trial |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375789/ https://www.ncbi.nlm.nih.gov/pubmed/34447172 http://dx.doi.org/10.4103/jpbs.JPBS_772_20 |
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