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Antimicrobial Efficacy of Different Pulp-Capping Materials against Enterococcus faecalis: An In vitro Study
AIM: The present study aims to assess the antimicrobial action of three different pulp-capping agents against Enterococcus faecalis. MATERIALS AND METHODS: Three pulp-capping agents were chosen for this study: Calcicur, mineral trioxide aggregate (MTA)-Angelus, and Dycal. The zone of inhibition prod...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375796/ https://www.ncbi.nlm.nih.gov/pubmed/34447163 http://dx.doi.org/10.4103/jpbs.JPBS_586_20 |
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author | Atom, Jenny Devi, Ningthoukhongjam Rati Lairenlakpam, Ronel Dafer Al Wadei, Mohammed Hussain Hakami, Abdulrahim R. BinShaya, Abdulkarim S. |
author_facet | Atom, Jenny Devi, Ningthoukhongjam Rati Lairenlakpam, Ronel Dafer Al Wadei, Mohammed Hussain Hakami, Abdulrahim R. BinShaya, Abdulkarim S. |
author_sort | Atom, Jenny |
collection | PubMed |
description | AIM: The present study aims to assess the antimicrobial action of three different pulp-capping agents against Enterococcus faecalis. MATERIALS AND METHODS: Three pulp-capping agents were chosen for this study: Calcicur, mineral trioxide aggregate (MTA)-Angelus, and Dycal. The zone of inhibition produced by these three pulp-capping agents was measured at 24 h and 72 h to assess their antimicrobial efficacy against E. faecalis. The agar diffusion method was used to examine the antimicrobial effect of pulp-capping agents. Mueller-Hinton agar plates were used to inoculate the microorganisms. Analysis of variance (ANOVA) and Tukey's post hoc tests were done to compare the different groups. P < 0.05 was considered as statistically significant. RESULTS: At 24 h, the highest zone of inhibition was found in MTA-Angelus (3.32 ± 0.11 mm), followed by Dycal (2.02 ± 0.46 mm) and Calcicur (1.84 ± 0.92 mm). After 72 h, MTA-Angelus demonstrated a zone of inhibition of 4.60 ± 0.22 mm, followed by Dycal (3.48 ± 0.74 mm) and Calcicur (2.90 ± 0.18 mm). ANOVA test showed a highly statistical significance. A statistically significant difference (P < 0.001) was shown between MTA-Angelus and Dycal. Calcicur did not show any significant difference. CONCLUSION: This trial found that the freshly mixed MTA-Angelus has a significantly superior antimicrobial effect against E. faecalis than Dycal and Calcicur. |
format | Online Article Text |
id | pubmed-8375796 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-83757962021-08-25 Antimicrobial Efficacy of Different Pulp-Capping Materials against Enterococcus faecalis: An In vitro Study Atom, Jenny Devi, Ningthoukhongjam Rati Lairenlakpam, Ronel Dafer Al Wadei, Mohammed Hussain Hakami, Abdulrahim R. BinShaya, Abdulkarim S. J Pharm Bioallied Sci Original Article AIM: The present study aims to assess the antimicrobial action of three different pulp-capping agents against Enterococcus faecalis. MATERIALS AND METHODS: Three pulp-capping agents were chosen for this study: Calcicur, mineral trioxide aggregate (MTA)-Angelus, and Dycal. The zone of inhibition produced by these three pulp-capping agents was measured at 24 h and 72 h to assess their antimicrobial efficacy against E. faecalis. The agar diffusion method was used to examine the antimicrobial effect of pulp-capping agents. Mueller-Hinton agar plates were used to inoculate the microorganisms. Analysis of variance (ANOVA) and Tukey's post hoc tests were done to compare the different groups. P < 0.05 was considered as statistically significant. RESULTS: At 24 h, the highest zone of inhibition was found in MTA-Angelus (3.32 ± 0.11 mm), followed by Dycal (2.02 ± 0.46 mm) and Calcicur (1.84 ± 0.92 mm). After 72 h, MTA-Angelus demonstrated a zone of inhibition of 4.60 ± 0.22 mm, followed by Dycal (3.48 ± 0.74 mm) and Calcicur (2.90 ± 0.18 mm). ANOVA test showed a highly statistical significance. A statistically significant difference (P < 0.001) was shown between MTA-Angelus and Dycal. Calcicur did not show any significant difference. CONCLUSION: This trial found that the freshly mixed MTA-Angelus has a significantly superior antimicrobial effect against E. faecalis than Dycal and Calcicur. Wolters Kluwer - Medknow 2021-06 2021-06-05 /pmc/articles/PMC8375796/ /pubmed/34447163 http://dx.doi.org/10.4103/jpbs.JPBS_586_20 Text en Copyright: © 2021 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Atom, Jenny Devi, Ningthoukhongjam Rati Lairenlakpam, Ronel Dafer Al Wadei, Mohammed Hussain Hakami, Abdulrahim R. BinShaya, Abdulkarim S. Antimicrobial Efficacy of Different Pulp-Capping Materials against Enterococcus faecalis: An In vitro Study |
title | Antimicrobial Efficacy of Different Pulp-Capping Materials against Enterococcus faecalis: An In vitro Study |
title_full | Antimicrobial Efficacy of Different Pulp-Capping Materials against Enterococcus faecalis: An In vitro Study |
title_fullStr | Antimicrobial Efficacy of Different Pulp-Capping Materials against Enterococcus faecalis: An In vitro Study |
title_full_unstemmed | Antimicrobial Efficacy of Different Pulp-Capping Materials against Enterococcus faecalis: An In vitro Study |
title_short | Antimicrobial Efficacy of Different Pulp-Capping Materials against Enterococcus faecalis: An In vitro Study |
title_sort | antimicrobial efficacy of different pulp-capping materials against enterococcus faecalis: an in vitro study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375796/ https://www.ncbi.nlm.nih.gov/pubmed/34447163 http://dx.doi.org/10.4103/jpbs.JPBS_586_20 |
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