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Antimicrobial Efficacy of Different Pulp-Capping Materials against Enterococcus faecalis: An In vitro Study

AIM: The present study aims to assess the antimicrobial action of three different pulp-capping agents against Enterococcus faecalis. MATERIALS AND METHODS: Three pulp-capping agents were chosen for this study: Calcicur, mineral trioxide aggregate (MTA)-Angelus, and Dycal. The zone of inhibition prod...

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Autores principales: Atom, Jenny, Devi, Ningthoukhongjam Rati, Lairenlakpam, Ronel, Dafer Al Wadei, Mohammed Hussain, Hakami, Abdulrahim R., BinShaya, Abdulkarim S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375796/
https://www.ncbi.nlm.nih.gov/pubmed/34447163
http://dx.doi.org/10.4103/jpbs.JPBS_586_20
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author Atom, Jenny
Devi, Ningthoukhongjam Rati
Lairenlakpam, Ronel
Dafer Al Wadei, Mohammed Hussain
Hakami, Abdulrahim R.
BinShaya, Abdulkarim S.
author_facet Atom, Jenny
Devi, Ningthoukhongjam Rati
Lairenlakpam, Ronel
Dafer Al Wadei, Mohammed Hussain
Hakami, Abdulrahim R.
BinShaya, Abdulkarim S.
author_sort Atom, Jenny
collection PubMed
description AIM: The present study aims to assess the antimicrobial action of three different pulp-capping agents against Enterococcus faecalis. MATERIALS AND METHODS: Three pulp-capping agents were chosen for this study: Calcicur, mineral trioxide aggregate (MTA)-Angelus, and Dycal. The zone of inhibition produced by these three pulp-capping agents was measured at 24 h and 72 h to assess their antimicrobial efficacy against E. faecalis. The agar diffusion method was used to examine the antimicrobial effect of pulp-capping agents. Mueller-Hinton agar plates were used to inoculate the microorganisms. Analysis of variance (ANOVA) and Tukey's post hoc tests were done to compare the different groups. P < 0.05 was considered as statistically significant. RESULTS: At 24 h, the highest zone of inhibition was found in MTA-Angelus (3.32 ± 0.11 mm), followed by Dycal (2.02 ± 0.46 mm) and Calcicur (1.84 ± 0.92 mm). After 72 h, MTA-Angelus demonstrated a zone of inhibition of 4.60 ± 0.22 mm, followed by Dycal (3.48 ± 0.74 mm) and Calcicur (2.90 ± 0.18 mm). ANOVA test showed a highly statistical significance. A statistically significant difference (P < 0.001) was shown between MTA-Angelus and Dycal. Calcicur did not show any significant difference. CONCLUSION: This trial found that the freshly mixed MTA-Angelus has a significantly superior antimicrobial effect against E. faecalis than Dycal and Calcicur.
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spelling pubmed-83757962021-08-25 Antimicrobial Efficacy of Different Pulp-Capping Materials against Enterococcus faecalis: An In vitro Study Atom, Jenny Devi, Ningthoukhongjam Rati Lairenlakpam, Ronel Dafer Al Wadei, Mohammed Hussain Hakami, Abdulrahim R. BinShaya, Abdulkarim S. J Pharm Bioallied Sci Original Article AIM: The present study aims to assess the antimicrobial action of three different pulp-capping agents against Enterococcus faecalis. MATERIALS AND METHODS: Three pulp-capping agents were chosen for this study: Calcicur, mineral trioxide aggregate (MTA)-Angelus, and Dycal. The zone of inhibition produced by these three pulp-capping agents was measured at 24 h and 72 h to assess their antimicrobial efficacy against E. faecalis. The agar diffusion method was used to examine the antimicrobial effect of pulp-capping agents. Mueller-Hinton agar plates were used to inoculate the microorganisms. Analysis of variance (ANOVA) and Tukey's post hoc tests were done to compare the different groups. P < 0.05 was considered as statistically significant. RESULTS: At 24 h, the highest zone of inhibition was found in MTA-Angelus (3.32 ± 0.11 mm), followed by Dycal (2.02 ± 0.46 mm) and Calcicur (1.84 ± 0.92 mm). After 72 h, MTA-Angelus demonstrated a zone of inhibition of 4.60 ± 0.22 mm, followed by Dycal (3.48 ± 0.74 mm) and Calcicur (2.90 ± 0.18 mm). ANOVA test showed a highly statistical significance. A statistically significant difference (P < 0.001) was shown between MTA-Angelus and Dycal. Calcicur did not show any significant difference. CONCLUSION: This trial found that the freshly mixed MTA-Angelus has a significantly superior antimicrobial effect against E. faecalis than Dycal and Calcicur. Wolters Kluwer - Medknow 2021-06 2021-06-05 /pmc/articles/PMC8375796/ /pubmed/34447163 http://dx.doi.org/10.4103/jpbs.JPBS_586_20 Text en Copyright: © 2021 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Atom, Jenny
Devi, Ningthoukhongjam Rati
Lairenlakpam, Ronel
Dafer Al Wadei, Mohammed Hussain
Hakami, Abdulrahim R.
BinShaya, Abdulkarim S.
Antimicrobial Efficacy of Different Pulp-Capping Materials against Enterococcus faecalis: An In vitro Study
title Antimicrobial Efficacy of Different Pulp-Capping Materials against Enterococcus faecalis: An In vitro Study
title_full Antimicrobial Efficacy of Different Pulp-Capping Materials against Enterococcus faecalis: An In vitro Study
title_fullStr Antimicrobial Efficacy of Different Pulp-Capping Materials against Enterococcus faecalis: An In vitro Study
title_full_unstemmed Antimicrobial Efficacy of Different Pulp-Capping Materials against Enterococcus faecalis: An In vitro Study
title_short Antimicrobial Efficacy of Different Pulp-Capping Materials against Enterococcus faecalis: An In vitro Study
title_sort antimicrobial efficacy of different pulp-capping materials against enterococcus faecalis: an in vitro study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375796/
https://www.ncbi.nlm.nih.gov/pubmed/34447163
http://dx.doi.org/10.4103/jpbs.JPBS_586_20
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