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Cariostatic Efficacy of Cinnamon Water Extract on Streptococcus mutans: An In vitro Study

BACKGROUND: Dental caries is a chronic, widespread, and infectious disease affecting the large population. Anticariogenic effects of different herbs and natural products are observed, cinnamon among these, showed the ability to inhibit Streptococcus mutans biofilm. OBJECTIVES: The aim of this study...

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Autores principales: Mala, Nutan, Sonal, Sinha, Kumar, Amit, Choudhary, Harsh Vardhan, Songara, Prafulla, Ramesh, Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375898/
https://www.ncbi.nlm.nih.gov/pubmed/34447078
http://dx.doi.org/10.4103/jpbs.JPBS_677_20
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author Mala, Nutan
Sonal, Sinha
Kumar, Amit
Choudhary, Harsh Vardhan
Songara, Prafulla
Ramesh, Kumar
author_facet Mala, Nutan
Sonal, Sinha
Kumar, Amit
Choudhary, Harsh Vardhan
Songara, Prafulla
Ramesh, Kumar
author_sort Mala, Nutan
collection PubMed
description BACKGROUND: Dental caries is a chronic, widespread, and infectious disease affecting the large population. Anticariogenic effects of different herbs and natural products are observed, cinnamon among these, showed the ability to inhibit Streptococcus mutans biofilm. OBJECTIVES: The aim of this study was to assess the cinnamon water extract use on nicotine exposed S. mutans biolfilms. MATERIALS AND METHODS: Microtiter plates having S. mutans culture were treated using varying nicotine concentration range (0–32 mg/ml). These were then either subjected to cinnamon water (2.5 mg/ml) extract or no treatment and analyzed using a spectrophotometer to see planktonic growth, total growth absorbance, and biofilm formation. RESULTS: About 2.5 mg/ml of cinnamon water inhibits the S. mutans biofilm (nicotine-induced) considerably at various nicotine levels (0–32 mg/ml). CONCLUSION: Cinnamon water extract has a powerful inhibitory effect for S. mutans growth. Nicotine-induced S. mutans growth is markedly reduced by treating with cinnamon water extract.
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spelling pubmed-83758982021-08-25 Cariostatic Efficacy of Cinnamon Water Extract on Streptococcus mutans: An In vitro Study Mala, Nutan Sonal, Sinha Kumar, Amit Choudhary, Harsh Vardhan Songara, Prafulla Ramesh, Kumar J Pharm Bioallied Sci Original Article BACKGROUND: Dental caries is a chronic, widespread, and infectious disease affecting the large population. Anticariogenic effects of different herbs and natural products are observed, cinnamon among these, showed the ability to inhibit Streptococcus mutans biofilm. OBJECTIVES: The aim of this study was to assess the cinnamon water extract use on nicotine exposed S. mutans biolfilms. MATERIALS AND METHODS: Microtiter plates having S. mutans culture were treated using varying nicotine concentration range (0–32 mg/ml). These were then either subjected to cinnamon water (2.5 mg/ml) extract or no treatment and analyzed using a spectrophotometer to see planktonic growth, total growth absorbance, and biofilm formation. RESULTS: About 2.5 mg/ml of cinnamon water inhibits the S. mutans biofilm (nicotine-induced) considerably at various nicotine levels (0–32 mg/ml). CONCLUSION: Cinnamon water extract has a powerful inhibitory effect for S. mutans growth. Nicotine-induced S. mutans growth is markedly reduced by treating with cinnamon water extract. Wolters Kluwer - Medknow 2021-06 2021-06-05 /pmc/articles/PMC8375898/ /pubmed/34447078 http://dx.doi.org/10.4103/jpbs.JPBS_677_20 Text en Copyright: © 2021 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Mala, Nutan
Sonal, Sinha
Kumar, Amit
Choudhary, Harsh Vardhan
Songara, Prafulla
Ramesh, Kumar
Cariostatic Efficacy of Cinnamon Water Extract on Streptococcus mutans: An In vitro Study
title Cariostatic Efficacy of Cinnamon Water Extract on Streptococcus mutans: An In vitro Study
title_full Cariostatic Efficacy of Cinnamon Water Extract on Streptococcus mutans: An In vitro Study
title_fullStr Cariostatic Efficacy of Cinnamon Water Extract on Streptococcus mutans: An In vitro Study
title_full_unstemmed Cariostatic Efficacy of Cinnamon Water Extract on Streptococcus mutans: An In vitro Study
title_short Cariostatic Efficacy of Cinnamon Water Extract on Streptococcus mutans: An In vitro Study
title_sort cariostatic efficacy of cinnamon water extract on streptococcus mutans: an in vitro study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375898/
https://www.ncbi.nlm.nih.gov/pubmed/34447078
http://dx.doi.org/10.4103/jpbs.JPBS_677_20
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