Cargando…
Cariostatic Efficacy of Cinnamon Water Extract on Streptococcus mutans: An In vitro Study
BACKGROUND: Dental caries is a chronic, widespread, and infectious disease affecting the large population. Anticariogenic effects of different herbs and natural products are observed, cinnamon among these, showed the ability to inhibit Streptococcus mutans biofilm. OBJECTIVES: The aim of this study...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375898/ https://www.ncbi.nlm.nih.gov/pubmed/34447078 http://dx.doi.org/10.4103/jpbs.JPBS_677_20 |
_version_ | 1783740392261287936 |
---|---|
author | Mala, Nutan Sonal, Sinha Kumar, Amit Choudhary, Harsh Vardhan Songara, Prafulla Ramesh, Kumar |
author_facet | Mala, Nutan Sonal, Sinha Kumar, Amit Choudhary, Harsh Vardhan Songara, Prafulla Ramesh, Kumar |
author_sort | Mala, Nutan |
collection | PubMed |
description | BACKGROUND: Dental caries is a chronic, widespread, and infectious disease affecting the large population. Anticariogenic effects of different herbs and natural products are observed, cinnamon among these, showed the ability to inhibit Streptococcus mutans biofilm. OBJECTIVES: The aim of this study was to assess the cinnamon water extract use on nicotine exposed S. mutans biolfilms. MATERIALS AND METHODS: Microtiter plates having S. mutans culture were treated using varying nicotine concentration range (0–32 mg/ml). These were then either subjected to cinnamon water (2.5 mg/ml) extract or no treatment and analyzed using a spectrophotometer to see planktonic growth, total growth absorbance, and biofilm formation. RESULTS: About 2.5 mg/ml of cinnamon water inhibits the S. mutans biofilm (nicotine-induced) considerably at various nicotine levels (0–32 mg/ml). CONCLUSION: Cinnamon water extract has a powerful inhibitory effect for S. mutans growth. Nicotine-induced S. mutans growth is markedly reduced by treating with cinnamon water extract. |
format | Online Article Text |
id | pubmed-8375898 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-83758982021-08-25 Cariostatic Efficacy of Cinnamon Water Extract on Streptococcus mutans: An In vitro Study Mala, Nutan Sonal, Sinha Kumar, Amit Choudhary, Harsh Vardhan Songara, Prafulla Ramesh, Kumar J Pharm Bioallied Sci Original Article BACKGROUND: Dental caries is a chronic, widespread, and infectious disease affecting the large population. Anticariogenic effects of different herbs and natural products are observed, cinnamon among these, showed the ability to inhibit Streptococcus mutans biofilm. OBJECTIVES: The aim of this study was to assess the cinnamon water extract use on nicotine exposed S. mutans biolfilms. MATERIALS AND METHODS: Microtiter plates having S. mutans culture were treated using varying nicotine concentration range (0–32 mg/ml). These were then either subjected to cinnamon water (2.5 mg/ml) extract or no treatment and analyzed using a spectrophotometer to see planktonic growth, total growth absorbance, and biofilm formation. RESULTS: About 2.5 mg/ml of cinnamon water inhibits the S. mutans biofilm (nicotine-induced) considerably at various nicotine levels (0–32 mg/ml). CONCLUSION: Cinnamon water extract has a powerful inhibitory effect for S. mutans growth. Nicotine-induced S. mutans growth is markedly reduced by treating with cinnamon water extract. Wolters Kluwer - Medknow 2021-06 2021-06-05 /pmc/articles/PMC8375898/ /pubmed/34447078 http://dx.doi.org/10.4103/jpbs.JPBS_677_20 Text en Copyright: © 2021 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Mala, Nutan Sonal, Sinha Kumar, Amit Choudhary, Harsh Vardhan Songara, Prafulla Ramesh, Kumar Cariostatic Efficacy of Cinnamon Water Extract on Streptococcus mutans: An In vitro Study |
title | Cariostatic Efficacy of Cinnamon Water Extract on Streptococcus mutans: An In vitro Study |
title_full | Cariostatic Efficacy of Cinnamon Water Extract on Streptococcus mutans: An In vitro Study |
title_fullStr | Cariostatic Efficacy of Cinnamon Water Extract on Streptococcus mutans: An In vitro Study |
title_full_unstemmed | Cariostatic Efficacy of Cinnamon Water Extract on Streptococcus mutans: An In vitro Study |
title_short | Cariostatic Efficacy of Cinnamon Water Extract on Streptococcus mutans: An In vitro Study |
title_sort | cariostatic efficacy of cinnamon water extract on streptococcus mutans: an in vitro study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375898/ https://www.ncbi.nlm.nih.gov/pubmed/34447078 http://dx.doi.org/10.4103/jpbs.JPBS_677_20 |
work_keys_str_mv | AT malanutan cariostaticefficacyofcinnamonwaterextractonstreptococcusmutansaninvitrostudy AT sonalsinha cariostaticefficacyofcinnamonwaterextractonstreptococcusmutansaninvitrostudy AT kumaramit cariostaticefficacyofcinnamonwaterextractonstreptococcusmutansaninvitrostudy AT choudharyharshvardhan cariostaticefficacyofcinnamonwaterextractonstreptococcusmutansaninvitrostudy AT songaraprafulla cariostaticefficacyofcinnamonwaterextractonstreptococcusmutansaninvitrostudy AT rameshkumar cariostaticefficacyofcinnamonwaterextractonstreptococcusmutansaninvitrostudy |