Cargando…
An application of the ensemble Kalman filter in epidemiological modelling
Since the novel coronavirus (COVID-19) outbreak in China, and due to the open accessibility of COVID-19 data, several researchers and modellers revisited the classical epidemiological models to evaluate their practical applicability. While mathematical compartmental models can predict various contag...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376003/ https://www.ncbi.nlm.nih.gov/pubmed/34411132 http://dx.doi.org/10.1371/journal.pone.0256227 |
_version_ | 1783740417431306240 |
---|---|
author | Lal, Rajnesh Huang, Weidong Li, Zhenquan |
author_facet | Lal, Rajnesh Huang, Weidong Li, Zhenquan |
author_sort | Lal, Rajnesh |
collection | PubMed |
description | Since the novel coronavirus (COVID-19) outbreak in China, and due to the open accessibility of COVID-19 data, several researchers and modellers revisited the classical epidemiological models to evaluate their practical applicability. While mathematical compartmental models can predict various contagious viruses’ dynamics, their efficiency depends on the model parameters. Recently, several parameter estimation methods have been proposed for different models. In this study, we evaluated the Ensemble Kalman filter’s performance (EnKF) in the estimation of time-varying model parameters with synthetic data and the real COVID-19 data of Hubei province, China. Contrary to the previous works, in the current study, the effect of damping factors on an augmented EnKF is studied. An augmented EnKF algorithm is provided, and we present how the filter performs in estimating models using uncertain observational (reported) data. Results obtained confirm that the augumented-EnKF approach can provide reliable model parameter estimates. Additionally, there was a good fit of profiles between model simulation and the reported COVID-19 data confirming the possibility of using the augmented-EnKF approach for reliable model parameter estimation. |
format | Online Article Text |
id | pubmed-8376003 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-83760032021-08-20 An application of the ensemble Kalman filter in epidemiological modelling Lal, Rajnesh Huang, Weidong Li, Zhenquan PLoS One Research Article Since the novel coronavirus (COVID-19) outbreak in China, and due to the open accessibility of COVID-19 data, several researchers and modellers revisited the classical epidemiological models to evaluate their practical applicability. While mathematical compartmental models can predict various contagious viruses’ dynamics, their efficiency depends on the model parameters. Recently, several parameter estimation methods have been proposed for different models. In this study, we evaluated the Ensemble Kalman filter’s performance (EnKF) in the estimation of time-varying model parameters with synthetic data and the real COVID-19 data of Hubei province, China. Contrary to the previous works, in the current study, the effect of damping factors on an augmented EnKF is studied. An augmented EnKF algorithm is provided, and we present how the filter performs in estimating models using uncertain observational (reported) data. Results obtained confirm that the augumented-EnKF approach can provide reliable model parameter estimates. Additionally, there was a good fit of profiles between model simulation and the reported COVID-19 data confirming the possibility of using the augmented-EnKF approach for reliable model parameter estimation. Public Library of Science 2021-08-19 /pmc/articles/PMC8376003/ /pubmed/34411132 http://dx.doi.org/10.1371/journal.pone.0256227 Text en © 2021 Lal et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Lal, Rajnesh Huang, Weidong Li, Zhenquan An application of the ensemble Kalman filter in epidemiological modelling |
title | An application of the ensemble Kalman filter in epidemiological modelling |
title_full | An application of the ensemble Kalman filter in epidemiological modelling |
title_fullStr | An application of the ensemble Kalman filter in epidemiological modelling |
title_full_unstemmed | An application of the ensemble Kalman filter in epidemiological modelling |
title_short | An application of the ensemble Kalman filter in epidemiological modelling |
title_sort | application of the ensemble kalman filter in epidemiological modelling |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376003/ https://www.ncbi.nlm.nih.gov/pubmed/34411132 http://dx.doi.org/10.1371/journal.pone.0256227 |
work_keys_str_mv | AT lalrajnesh anapplicationoftheensemblekalmanfilterinepidemiologicalmodelling AT huangweidong anapplicationoftheensemblekalmanfilterinepidemiologicalmodelling AT lizhenquan anapplicationoftheensemblekalmanfilterinepidemiologicalmodelling AT lalrajnesh applicationoftheensemblekalmanfilterinepidemiologicalmodelling AT huangweidong applicationoftheensemblekalmanfilterinepidemiologicalmodelling AT lizhenquan applicationoftheensemblekalmanfilterinepidemiologicalmodelling |