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Seasonality and weather dependance of Acinetobacter baumannii complex bloodstream infections in different climates in Brazil
Recent studies report seasonality in healthcare-associated infections, especially those caused by Acinetobacter baumannii complex. We conducted an ecologic study aimed at analyzing the impact of seasons, weather parameters and climate control on the incidence and carbapenem-resistance in A. baumanni...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376013/ https://www.ncbi.nlm.nih.gov/pubmed/34411123 http://dx.doi.org/10.1371/journal.pone.0255593 |
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author | Filho, Sebastião Pires Ferreira Pereira, Milca Severino Nobre Rodrigues, Jorge Luiz Guimarães, Raul Borges Ribeiro da Cunha, Antônio Corrente, José Eduardo Campos Pignatari, Antônio Carlos Fortaleza, Carlos Magno Castelo Branco |
author_facet | Filho, Sebastião Pires Ferreira Pereira, Milca Severino Nobre Rodrigues, Jorge Luiz Guimarães, Raul Borges Ribeiro da Cunha, Antônio Corrente, José Eduardo Campos Pignatari, Antônio Carlos Fortaleza, Carlos Magno Castelo Branco |
author_sort | Filho, Sebastião Pires Ferreira |
collection | PubMed |
description | Recent studies report seasonality in healthcare-associated infections, especially those caused by Acinetobacter baumannii complex. We conducted an ecologic study aimed at analyzing the impact of seasons, weather parameters and climate control on the incidence and carbapenem-resistance in A. baumannii complex bloodstream infections (ABBSI) in hospitals from regions with different climates in Brazil. We studied monthly incidence rates (years 2006–2015) of ABBSI from hospitals in cities from different macro-regions in Brazil: Fortaleza (Ceará State, Northeast region), Goiânia (Goiás State, Middle-west) and Botucatu (São Paulo State, Southeast). Box-Jenkins models were fitted to assess seasonality, and the impact of weather parameters was analyzed in Poisson Regression models. Separate analyses were performed for carbapenem-resistant versus carbapenem-susceptible isolates, as well as for infections occurring in climate-controlled intensive care units (ICUs) versus non-climate-controlled wards. Seasonality was identified for ABSSI ICUs in the Hospitals from Botucatu and Goiânia. In the Botucatu hospital, where there was overall seasonality for both resistance groups, as well as for wards without climate control. In that hospital, the overall incidence was associated with higher temperature (incidence rate ratio for each Celsius degree, 1.05; 95% Confidence Interval, 1.01–1.09; P = 0.006). Weather parameters were not associated with ABBSI in the hospitals from Goiânia and Fortaleza. In conclusion, seasonality was found in the hospitals with higher ABBSI incidence and located in regions with greater thermal amplitude. Strict temperature control may be a tool for prevention of A. baumanii infections in healthcare settings. |
format | Online Article Text |
id | pubmed-8376013 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-83760132021-08-20 Seasonality and weather dependance of Acinetobacter baumannii complex bloodstream infections in different climates in Brazil Filho, Sebastião Pires Ferreira Pereira, Milca Severino Nobre Rodrigues, Jorge Luiz Guimarães, Raul Borges Ribeiro da Cunha, Antônio Corrente, José Eduardo Campos Pignatari, Antônio Carlos Fortaleza, Carlos Magno Castelo Branco PLoS One Research Article Recent studies report seasonality in healthcare-associated infections, especially those caused by Acinetobacter baumannii complex. We conducted an ecologic study aimed at analyzing the impact of seasons, weather parameters and climate control on the incidence and carbapenem-resistance in A. baumannii complex bloodstream infections (ABBSI) in hospitals from regions with different climates in Brazil. We studied monthly incidence rates (years 2006–2015) of ABBSI from hospitals in cities from different macro-regions in Brazil: Fortaleza (Ceará State, Northeast region), Goiânia (Goiás State, Middle-west) and Botucatu (São Paulo State, Southeast). Box-Jenkins models were fitted to assess seasonality, and the impact of weather parameters was analyzed in Poisson Regression models. Separate analyses were performed for carbapenem-resistant versus carbapenem-susceptible isolates, as well as for infections occurring in climate-controlled intensive care units (ICUs) versus non-climate-controlled wards. Seasonality was identified for ABSSI ICUs in the Hospitals from Botucatu and Goiânia. In the Botucatu hospital, where there was overall seasonality for both resistance groups, as well as for wards without climate control. In that hospital, the overall incidence was associated with higher temperature (incidence rate ratio for each Celsius degree, 1.05; 95% Confidence Interval, 1.01–1.09; P = 0.006). Weather parameters were not associated with ABBSI in the hospitals from Goiânia and Fortaleza. In conclusion, seasonality was found in the hospitals with higher ABBSI incidence and located in regions with greater thermal amplitude. Strict temperature control may be a tool for prevention of A. baumanii infections in healthcare settings. Public Library of Science 2021-08-19 /pmc/articles/PMC8376013/ /pubmed/34411123 http://dx.doi.org/10.1371/journal.pone.0255593 Text en © 2021 Filho et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Filho, Sebastião Pires Ferreira Pereira, Milca Severino Nobre Rodrigues, Jorge Luiz Guimarães, Raul Borges Ribeiro da Cunha, Antônio Corrente, José Eduardo Campos Pignatari, Antônio Carlos Fortaleza, Carlos Magno Castelo Branco Seasonality and weather dependance of Acinetobacter baumannii complex bloodstream infections in different climates in Brazil |
title | Seasonality and weather dependance of Acinetobacter baumannii complex bloodstream infections in different climates in Brazil |
title_full | Seasonality and weather dependance of Acinetobacter baumannii complex bloodstream infections in different climates in Brazil |
title_fullStr | Seasonality and weather dependance of Acinetobacter baumannii complex bloodstream infections in different climates in Brazil |
title_full_unstemmed | Seasonality and weather dependance of Acinetobacter baumannii complex bloodstream infections in different climates in Brazil |
title_short | Seasonality and weather dependance of Acinetobacter baumannii complex bloodstream infections in different climates in Brazil |
title_sort | seasonality and weather dependance of acinetobacter baumannii complex bloodstream infections in different climates in brazil |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376013/ https://www.ncbi.nlm.nih.gov/pubmed/34411123 http://dx.doi.org/10.1371/journal.pone.0255593 |
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