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NAD(+) pool depletion as a signal for the Rex regulon involved in Streptococcus agalactiae virulence
In many Gram-positive bacteria, the redox-sensing transcriptional repressor Rex controls central carbon and energy metabolism by sensing the intra cellular balance between the reduced and oxidized forms of nicotinamide adenine dinucleotide; the NADH/NAD(+) ratio. Here, we report high-resolution crys...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376106/ https://www.ncbi.nlm.nih.gov/pubmed/34370789 http://dx.doi.org/10.1371/journal.ppat.1009791 |