NAD(+) pool depletion as a signal for the Rex regulon involved in Streptococcus agalactiae virulence

In many Gram-positive bacteria, the redox-sensing transcriptional repressor Rex controls central carbon and energy metabolism by sensing the intra cellular balance between the reduced and oxidized forms of nicotinamide adenine dinucleotide; the NADH/NAD(+) ratio. Here, we report high-resolution crys...

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Detalles Bibliográficos
Autores principales: Franza, Thierry, Rogstam, Annika, Thiyagarajan, Saravanamuthu, Sullivan, Matthew J., Derré-Bobillot, Aurelie, Bauer, Mikael C., Goh, Kelvin G. K., Da Cunha, Violette, Glaser, Philippe, Logan, Derek T., Ulett, Glen C., von Wachenfeldt, Claes, Gaudu, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376106/
https://www.ncbi.nlm.nih.gov/pubmed/34370789
http://dx.doi.org/10.1371/journal.ppat.1009791

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