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Multiscale model of hepatitis C virus dynamics in plasma and liver following combination therapy

This work explores the application of a physiologically structured population (PSP) framework in modeling hepatitis C virus (HCV) kinetics. To do so, a model was developed for the viral RNA load in plasma and liver as observed in 15 patients treated with a combination therapy of pegylated interferon...

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Detalles Bibliográficos
Autores principales: Woot de Trixhe, Xavier, Krzyzanski, Wojciech, Vermeulen, An, Perez‐Ruixo, Juan José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376145/
https://www.ncbi.nlm.nih.gov/pubmed/34296543
http://dx.doi.org/10.1002/psp4.12604

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