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Multiscale model of hepatitis C virus dynamics in plasma and liver following combination therapy
This work explores the application of a physiologically structured population (PSP) framework in modeling hepatitis C virus (HCV) kinetics. To do so, a model was developed for the viral RNA load in plasma and liver as observed in 15 patients treated with a combination therapy of pegylated interferon...
Autores principales: | Woot de Trixhe, Xavier, Krzyzanski, Wojciech, Vermeulen, An, Perez‐Ruixo, Juan José |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376145/ https://www.ncbi.nlm.nih.gov/pubmed/34296543 http://dx.doi.org/10.1002/psp4.12604 |
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