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A GUNN RAT MODEL OF PRETERM HYPERBILIRUBINEMIA

BACKGROUND: The impact of bilirubin in preterm infants is poorly understood. An animal model would assist in improving understanding. The Gunn rat lacks uridine diphosphate-glucuronylsyl transferase 1 and can be made acutely hyperbilirubinemic by injection of sulfodimethoxine (sulfa), a drug that di...

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Detalles Bibliográficos
Autores principales: Waddell, Jaylyn, He, Min, Tang, Ningfeng, Rizzuto, Christian, Bearer, Cynthia F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376196/
https://www.ncbi.nlm.nih.gov/pubmed/31578041
http://dx.doi.org/10.1038/s41390-019-0599-x