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A multi-approach and multi-scale platform to model CD4+ T cells responding to infections
Immune responses rely on a complex adaptive system in which the body and infections interact at multiple scales and in different compartments. We developed a modular model of CD4+ T cells, which uses four modeling approaches to integrate processes at three spatial scales in different tissues. In eac...
Autores principales: | Wertheim, Kenneth Y., Puniya, Bhanwar Lal, La Fleur, Alyssa, Shah, Ab Rauf, Barberis, Matteo, Helikar, Tomáš |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376204/ https://www.ncbi.nlm.nih.gov/pubmed/34343169 http://dx.doi.org/10.1371/journal.pcbi.1009209 |
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