TMEM120A is a coenzyme A-binding membrane protein with structural similarities to ELOVL fatty acid elongase

TMEM120A, also named as TACAN, is a novel membrane protein highly conserved in vertebrates and was recently proposed to be a mechanosensitive channel involved in sensing mechanical pain. Here we present the single-particle cryogenic electron microscopy (cryo-EM) structure of human TMEM120A, which fo...

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Detalles Bibliográficos
Autores principales: Xue, Jing, Han, Yan, Baniasadi, Hamid, Zeng, Weizhong, Pei, Jimin, Grishin, Nick V, Wang, Junmei, Tu, Benjamin P, Jiang, Youxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376247/
https://www.ncbi.nlm.nih.gov/pubmed/34374645
http://dx.doi.org/10.7554/eLife.71220

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