Cargando…

Tonic interferon restricts pathogenic IL-17-driven inflammatory disease via balancing the microbiome

Maintenance of immune homeostasis involves a synergistic relationship between the host and the microbiome. Canonical interferon (IFN) signaling controls responses to acute microbial infection, through engagement of the STAT1 transcription factor. However, the contribution of tonic levels of IFN to i...

Descripción completa

Detalles Bibliográficos
Autores principales: Marié, Isabelle J, Brambilla, Lara, Azzouz, Doua, Chen, Ze, Baracho, Gisele V, Arnett, Azlann, Li, Haiyan S, Liu, Weiguo, Cimmino, Luisa, Chattopadhyay, Pratip, Silverman, Gregg, Watowich, Stephanie S, Khor, Bernard, Levy, David E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376249/
https://www.ncbi.nlm.nih.gov/pubmed/34378531
http://dx.doi.org/10.7554/eLife.68371