Functional development of a V3/glycan-specific broadly neutralizing antibody isolated from a case of HIV superinfection

Stimulating broadly neutralizing antibodies (bnAbs) directly from germline remains a barrier for HIV vaccines. HIV superinfection elicits bnAbs more frequently than single infection, providing clues of how to elicit such responses. We used longitudinal antibody sequencing and structural studies to c...

Descripción completa

Detalles Bibliográficos
Autores principales: Shipley, Mackenzie M, Mangala Prasad, Vidya, Doepker, Laura E, Dingens, Adam, Ralph, Duncan K, Harkins, Elias, Dhar, Amrit, Arenz, Dana, Chohan, Vrasha, Weight, Haidyn, Mandaliya, Kishor, Bloom, Jesse D, Matsen, Frederick A, Lee, Kelly K, Overbaugh, Julie M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376252/
https://www.ncbi.nlm.nih.gov/pubmed/34263727
http://dx.doi.org/10.7554/eLife.68110

Ejemplares similares

Ejemplares similares