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A Case of an Extremely Low Birth Weight Infant with Morganella morganii Bacteremia and Peritonitis

We describe a case of late onset Morganella morganii sepsis in an extremely low birth weight male neonate born at 23 and 4/7 weeks gestational age to a 30-year-old primigravid mother due to preterm labor. The mother was otherwise healthy with an unremarkable prenatal course. She received steroids an...

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Autores principales: Pham, Betty, Denslow, Anne, Mikhael, Michel, Lim, Jina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical Publishers, Inc. 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376401/
https://www.ncbi.nlm.nih.gov/pubmed/34422454
http://dx.doi.org/10.1055/s-0041-1732407
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author Pham, Betty
Denslow, Anne
Mikhael, Michel
Lim, Jina
author_facet Pham, Betty
Denslow, Anne
Mikhael, Michel
Lim, Jina
author_sort Pham, Betty
collection PubMed
description We describe a case of late onset Morganella morganii sepsis in an extremely low birth weight male neonate born at 23 and 4/7 weeks gestational age to a 30-year-old primigravid mother due to preterm labor. The mother was otherwise healthy with an unremarkable prenatal course. She received steroids and ampicillin prior to delivery. While initial blood cultures were negative, at day of life 4, the neonate developed signs of sepsis with leukocytosis and bandemia, and subsequent blood culture demonstrated growth of M. morganii . The patient then had spontaneous intestinal perforation on day of life 8 with peritoneal cultures growing M. morganii . The infant responded to standard therapy and survived to discharge, with few mild developmental delays upon outpatient follow-up. While M. morganii has been demonstrated in the neonatal population, it generally causes early onset sepsis and is associated with high mortality in preterm neonates. Here, we present this case of late onset neonatal sepsis with M. morganii complicated by spontaneous intestinal perforation, with survival in a 23 weeks gestation infant.
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spelling pubmed-83764012021-08-20 A Case of an Extremely Low Birth Weight Infant with Morganella morganii Bacteremia and Peritonitis Pham, Betty Denslow, Anne Mikhael, Michel Lim, Jina AJP Rep We describe a case of late onset Morganella morganii sepsis in an extremely low birth weight male neonate born at 23 and 4/7 weeks gestational age to a 30-year-old primigravid mother due to preterm labor. The mother was otherwise healthy with an unremarkable prenatal course. She received steroids and ampicillin prior to delivery. While initial blood cultures were negative, at day of life 4, the neonate developed signs of sepsis with leukocytosis and bandemia, and subsequent blood culture demonstrated growth of M. morganii . The patient then had spontaneous intestinal perforation on day of life 8 with peritoneal cultures growing M. morganii . The infant responded to standard therapy and survived to discharge, with few mild developmental delays upon outpatient follow-up. While M. morganii has been demonstrated in the neonatal population, it generally causes early onset sepsis and is associated with high mortality in preterm neonates. Here, we present this case of late onset neonatal sepsis with M. morganii complicated by spontaneous intestinal perforation, with survival in a 23 weeks gestation infant. Thieme Medical Publishers, Inc. 2021-04 2021-08-19 /pmc/articles/PMC8376401/ /pubmed/34422454 http://dx.doi.org/10.1055/s-0041-1732407 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Pham, Betty
Denslow, Anne
Mikhael, Michel
Lim, Jina
A Case of an Extremely Low Birth Weight Infant with Morganella morganii Bacteremia and Peritonitis
title A Case of an Extremely Low Birth Weight Infant with Morganella morganii Bacteremia and Peritonitis
title_full A Case of an Extremely Low Birth Weight Infant with Morganella morganii Bacteremia and Peritonitis
title_fullStr A Case of an Extremely Low Birth Weight Infant with Morganella morganii Bacteremia and Peritonitis
title_full_unstemmed A Case of an Extremely Low Birth Weight Infant with Morganella morganii Bacteremia and Peritonitis
title_short A Case of an Extremely Low Birth Weight Infant with Morganella morganii Bacteremia and Peritonitis
title_sort case of an extremely low birth weight infant with morganella morganii bacteremia and peritonitis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376401/
https://www.ncbi.nlm.nih.gov/pubmed/34422454
http://dx.doi.org/10.1055/s-0041-1732407
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