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Schizophrenia and Hyperostosis Frontalis Interna with History of Head Injury

Hyperostosis frontalis interna is an irregular thickening of the frontal bone. Its etiology is unknown. It has been rarely linked with schizophrenia and head injury. Case Presentation. We describe an unusual case of a 44-year-old female with schizophrenia and hyperostosis frontalis interna having a...

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Autor principal: Elghazouani, Fatima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376403/
https://www.ncbi.nlm.nih.gov/pubmed/34422059
http://dx.doi.org/10.1155/2021/6634640
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author Elghazouani, Fatima
author_facet Elghazouani, Fatima
author_sort Elghazouani, Fatima
collection PubMed
description Hyperostosis frontalis interna is an irregular thickening of the frontal bone. Its etiology is unknown. It has been rarely linked with schizophrenia and head injury. Case Presentation. We describe an unusual case of a 44-year-old female with schizophrenia and hyperostosis frontalis interna having a history of head trauma. At the age of 3 years, she had a head injury that could be classified as mild traumatic brain injury. She presents a family history of schizophrenia. She was admitted for resistant schizophrenic disorder. The cranial computed tomography showed bilateral and asymmetrical hyperostosis of the frontal bone that was more pronounced on the right side. This corresponds to the impact of the trauma with frontal atrophy without any metabolic or endocrinal abnormalities. Conclusion. We surmise that the long-term pathological effects of traumatic brain injury, including hyperostosis frontalis interna, are likely to interact with genetic vulnerability and may lead to schizophrenic disorder.
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spelling pubmed-83764032021-08-20 Schizophrenia and Hyperostosis Frontalis Interna with History of Head Injury Elghazouani, Fatima Case Rep Med Case Report Hyperostosis frontalis interna is an irregular thickening of the frontal bone. Its etiology is unknown. It has been rarely linked with schizophrenia and head injury. Case Presentation. We describe an unusual case of a 44-year-old female with schizophrenia and hyperostosis frontalis interna having a history of head trauma. At the age of 3 years, she had a head injury that could be classified as mild traumatic brain injury. She presents a family history of schizophrenia. She was admitted for resistant schizophrenic disorder. The cranial computed tomography showed bilateral and asymmetrical hyperostosis of the frontal bone that was more pronounced on the right side. This corresponds to the impact of the trauma with frontal atrophy without any metabolic or endocrinal abnormalities. Conclusion. We surmise that the long-term pathological effects of traumatic brain injury, including hyperostosis frontalis interna, are likely to interact with genetic vulnerability and may lead to schizophrenic disorder. Hindawi 2021-08-12 /pmc/articles/PMC8376403/ /pubmed/34422059 http://dx.doi.org/10.1155/2021/6634640 Text en Copyright © 2021 Fatima Elghazouani. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Elghazouani, Fatima
Schizophrenia and Hyperostosis Frontalis Interna with History of Head Injury
title Schizophrenia and Hyperostosis Frontalis Interna with History of Head Injury
title_full Schizophrenia and Hyperostosis Frontalis Interna with History of Head Injury
title_fullStr Schizophrenia and Hyperostosis Frontalis Interna with History of Head Injury
title_full_unstemmed Schizophrenia and Hyperostosis Frontalis Interna with History of Head Injury
title_short Schizophrenia and Hyperostosis Frontalis Interna with History of Head Injury
title_sort schizophrenia and hyperostosis frontalis interna with history of head injury
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376403/
https://www.ncbi.nlm.nih.gov/pubmed/34422059
http://dx.doi.org/10.1155/2021/6634640
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