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In Vitro Comparison of the Internal Ribosomal Entry Site Activity from Rodent Hepacivirus and Pegivirus and Construction of Pseudoparticles

The 5′ untranslated region (5′ UTR) of rodent hepacivirus (RHV) and pegivirus (RPgV) contains sequence homology to the HCV type III internal ribosome entry sites (IRES). Utilizing a monocistronic expression vector with an RNA polymerase I promoter to drive transcription, we show cell-specific IRES t...

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Detalles Bibliográficos
Autores principales:	Sims, Stuart, Michaelsen, Kevin, Burkhard, Sara, Fraefel, Cornel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376455/ https://www.ncbi.nlm.nih.gov/pubmed/34422054 http://dx.doi.org/10.1155/2021/5569844

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