Whole-genome analysis of SARS-CoV-2 samples indicate no tissue specific genetic adaptation of the virus in COVID-19 patients’ upper and lower respiratory tract

Sample panels of SARS-CoV-2 cases were retrospectively whole-genome sequenced. In three individuals, samples of upper and lower respiratory tract resulted in identical sequences suggesting virus stability including the spike protein cleavage site. In a fourth case, low-level intra-host genomic evolu...

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Detalles Bibliográficos
Autores principales: Wylezich, Claudia, Schaller, Tina, Claus, Rainer, Hirschbühl, Klaus, Märkl, Bruno, Kling, Elisabeth, Spring, Oliver, Höper, Dirk, Schlegel, Jürgen, Beer, Martin, Dintner, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376524/
https://www.ncbi.nlm.nih.gov/pubmed/34536911
http://dx.doi.org/10.1016/j.diagmicrobio.2021.115520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376524/
https://www.ncbi.nlm.nih.gov/pubmed/34536911
http://dx.doi.org/10.1016/j.diagmicrobio.2021.115520

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