Cargando…

Whole-genome analysis of SARS-CoV-2 samples indicate no tissue specific genetic adaptation of the virus in COVID-19 patients’ upper and lower respiratory tract

Sample panels of SARS-CoV-2 cases were retrospectively whole-genome sequenced. In three individuals, samples of upper and lower respiratory tract resulted in identical sequences suggesting virus stability including the spike protein cleavage site. In a fourth case, low-level intra-host genomic evolu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wylezich, Claudia, Schaller, Tina, Claus, Rainer, Hirschbühl, Klaus, Märkl, Bruno, Kling, Elisabeth, Spring, Oliver, Höper, Dirk, Schlegel, Jürgen, Beer, Martin, Dintner, Sebastian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Authors. Published by Elsevier Inc. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376524/ https://www.ncbi.nlm.nih.gov/pubmed/34536911 http://dx.doi.org/10.1016/j.diagmicrobio.2021.115520

Ejemplares similares

Viral mapping in COVID-19 deceased in the Augsburg autopsy series of the first wave: A multiorgan and multimethodological approach
por: Hirschbühl, Klaus, et al.
Publicado: (2021)

Autopsy of patients with COVID-19: A balance of fear and curiosity
por: Hirschbühl, Klaus, et al.
Publicado: (2020)

High viral loads: what drives fatal cases of COVID-19 in vaccinees? – an autopsy study
por: Hirschbühl, Klaus, et al.
Publicado: (2022)

Quantitative multiorgan proteomics of fatal COVID‐19 uncovers tissue‐specific effects beyond inflammation
por: Schweizer, Lisa, et al.
Publicado: (2023)

Impaired Dendritic Cell Homing in COVID-19
por: Borcherding, Lukas, et al.
Publicado: (2021)

Loeffler 4.0: Diagnostic Metagenomics
por: Höper, Dirk, et al.
Publicado: (2017)

A Versatile Sample Processing Workflow for Metagenomic Pathogen Detection
por: Wylezich, Claudia, et al.
Publicado: (2018)

Meta-Ribosomalomics: RNA Sequencing Is an Unbiased Method for Parasite Detection of Different Sample Types
por: Wylezich, Claudia, et al.
Publicado: (2021)

Untargeted metagenomics shows a reliable performance for synchronous detection of parasites
por: Wylezich, Claudia, et al.
Publicado: (2020)

Next-generation diagnostics: virus capture facilitates a sensitive viral diagnosis for epizootic and zoonotic pathogens including SARS-CoV-2
por: Wylezich, Claudia, et al.
Publicado: (2021)

Reemergence of Lymphocytic Choriomeningitis Mammarenavirus, Germany
por: Mehl, Calvin, et al.
Publicado: (2023)

Revisiting Rustrela Virus: New Cases of Encephalitis and a Solution to the Capsid Enigma
por: Pfaff, Florian, et al.
Publicado: (2022)

African swine fever whole-genome sequencing—Quantity wanted but quality needed
por: Forth, Jan H., et al.
Publicado: (2020)

Synchronous melanosis of upper and lower urinary tract
por: Alzubaidi, Ahmad N., et al.
Publicado: (2022)

Primary Malignant Melanoma of the Genitourinary Tract with Upper and Lower Tracts Involvement
por: Sutton, Broderick, et al.
Publicado: (2013)

Clinical Aspects of Upper and Lower Respiratory Tract Infections
por: Grossman, Ronald F.
Publicado: (2012)

Bacterial topography of the upper and lower respiratory tract in pigs
por: Pirolo, Mattia, et al.
Publicado: (2023)

Compartmentalized Replication of SARS-Cov-2 in Upper vs. Lower Respiratory Tract Assessed by Whole Genome Quasispecies Analysis
por: Rueca, Martina, et al.
Publicado: (2020)

Nonbilharzial squamous cell carcinoma and transitional cell carcinoma with squamous differentiation of the lower and upper urinary tract
por: Rausch, Steffen, et al.
Publicado: (2012)

Whole-Genome Sequence of an African Swine Fever Virus Isolate from the Czech Republic
por: Forth, Jan H., et al.
Publicado: (2020)

Cefditoren in upper and lower community-acquired respiratory tract infections
por: Soriano, Francisco, et al.
Publicado: (2011)

Comparing microbiotas in the upper aerodigestive and lower respiratory tracts of lambs
por: Glendinning, Laura, et al.
Publicado: (2017)

Characterization of the upper and lower respiratory tract microbiota in Piedmontese calves
por: Nicola, Isabella, et al.
Publicado: (2017)

The upper and lower respiratory tract microbiome in severe aspiration pneumonia
por: Kitsios, Georgios D., et al.
Publicado: (2023)

Granulomatous dermatitis: a rare pitfall in lymphoma staging with [(18)F]FDG-PET/CT
por: Enke, Johanna S., et al.
Publicado: (2023)

Comparative Analysis of Whole-Genome Sequence of African Swine Fever Virus Belgium 2018/1
por: Forth, Jan H., et al.
Publicado: (2019)

Concurrent loss of MLH1, PMS2 and MSH6 immunoexpression in digestive system cancers indicating a widespread dysregulation in DNA repair processes
por: Reitsam, Nic Gabriel, et al.
Publicado: (2022)

Mast cells in lung damage of COVID‐19 autopsies: A descriptive study
por: Schaller, Tina, et al.
Publicado: (2022)

Differences in the development of autogenous nerves between the upper and lower urinary tract
por: CHEN, QIMIN, et al.
Publicado: (2013)

A Comprehensive Deep Sequencing Strategy for Full-Length Genomes of Influenza A
por: Höper, Dirk, et al.
Publicado: (2011)

RIEMS: a software pipeline for sensitive and comprehensive taxonomic classification of reads from metagenomics datasets
por: Scheuch, Matthias, et al.
Publicado: (2015)

Investigating Environmental Matrices for Use in Avian Influenza Virus Surveillance—Surface Water, Sediments, and Avian Fecal Samples
por: Ahrens, Ann Kathrin, et al.
Publicado: (2023)

Diagnosis of influenza from lower respiratory tract sampling after negative upper respiratory tract sampling
por: Bogoch, Isaac I., et al.
Publicado: (2013)

Oropharyngeal Dysphagia and Impaired Motility of the Upper Gastrointestinal Tract—Is There a Clinical Link in Neurocritical Care?
por: Muhle, Paul, et al.
Publicado: (2021)

Rhinovirus Genome Variation during Chronic Upper and Lower Respiratory Tract Infections
por: Tapparel, Caroline, et al.
Publicado: (2011)

Rhinovirus is an important pathogen in upper and lower respiratory tract infections in Mexican children
por: Aponte, Fernando E, et al.
Publicado: (2015)

Fungi-Induced Upper and Lower Respiratory Tract Allergic Diseases: One Entity
por: Barac, Aleksandra, et al.
Publicado: (2018)

Microscopic hematuria predicts lower stage in patients with upper tract urothelial carcinoma
por: Qi, Nienie, et al.
Publicado: (2018)

Comparison of Composition and Diversity of Bacterial Microbiome in Human Upper and Lower Respiratory Tract
por: Feng, Zhi-Hong, et al.
Publicado: (2017)

Snoring may transmit infectious aerosols from the upper to the lower respiratory tract
por: Bax, Adriaan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_bqs16bmqn29bq471iba7nk2oh5