Identification of hippocampal cortical microinfarcts on postmortem 3-T magnetic resonance imaging

Cortical microinfarcts (CMI) are increasingly recognized in the neurological community as a biomarker related to cognitive impairment and dementia. If their radiological depiction has been largely described in experimental settings using ultra-high-field magnetic resonance imaging (MRI), less is kno...

Descripción completa

Detalles Bibliográficos
Autores principales: Scheffler, Max, Salomir, Rares, Maturana, Enrique, Montandon, Marie-Louise, Kövari, Enikö V., Haller, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376696/
https://www.ncbi.nlm.nih.gov/pubmed/33909116
http://dx.doi.org/10.1007/s00234-021-02717-8
Descripción
Sumario:Cortical microinfarcts (CMI) are increasingly recognized in the neurological community as a biomarker related to cognitive impairment and dementia. If their radiological depiction has been largely described in experimental settings using ultra-high-field magnetic resonance imaging (MRI), less is known about their visibility on routinely used 3-T MRI. In this radiologic-pathologic correlation study, using 3-T post-mortem MRI, we searched for hippocampal CMI, in a double-blinded fashion, and found that only 4/36, or 11%, were clearly demonstrated on both radiological and histopathological exams.

Ejemplares similares