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A novel BMP-2–loaded hydroxyapatite/beta-tricalcium phosphate microsphere/hydrogel composite for bone regeneration
Although bone morphogenetic protein (BMP) has potent osteoinductivity, the potential adverse events attributed to its burst release prevent its widespread clinical application. Therefore, there is a strong need for BMP delivery systems that maximize osteoinductivity while preventing adverse effects....
Autores principales: | Tateiwa, Daisuke, Nakagawa, Shinichi, Tsukazaki, Hiroyuki, Okada, Rintaro, Kodama, Joe, Kushioka, Junichi, Bal, Zeynep, Ukon, Yuichiro, Hirai, Hiromasa, Kaito, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376985/ https://www.ncbi.nlm.nih.gov/pubmed/34413442 http://dx.doi.org/10.1038/s41598-021-96484-4 |
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